Protein Alignment Cyp6t3 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 520
• Identity: 115/520 - (22%)
• Similarity: 206/520 - (39%)
• Gaps: 75/520 - (14%)

  Fly     6 LLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYADPRNGQA 70
            ||||...|...:|..::....::..|. |||.|.    .|..:.......|:..::...|.....
Mouse    27 LLLLLFKTAQLYLHRQWLLSSTQQFPS-PPSHWL----FGHKILKDQDLQDILTRIKNFPSACPQ 86

  Fly    71 KIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGD-----PMGALTLPLAKYHHWKE 130
            .:.|..:    .:.|.||:.::.:        |.|.:....|.     |.....|.|.....|.:
Mouse    87 WLWGSKV----RIQVYDPDYMKLI--------LGRSDPKAHGSYRFLAPWIGRGLLLLDGQTWFQ 139

  Fly   131 SRQCMSQLFTSGRMR---DVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLYTTDVTGNL 192
            .|:.::..|....::   ::|...:..:....||.:.:      :..|.:.:...|.|.|.....
Mouse   140 HRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQ------DSTLEIFQHITLMTLDTIMKC 198

  Fly   193 FYSLNVGGLRRGRS-----ELITKTKELFNTNPRKVLDFMSVFFLPKWTGVLKPKV------FTE 246
            .:| :.|.::..|.     :.:.....||....|.:.....:.:.....|.|....      .|:
Mouse   199 AFS-HEGSVQLDRKYKSYIQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHTD 262

  Fly   247 DYARYMRHLVDDHHEPTKGDLINQLQHFQL---SRSSNHYSQHPDFVASQAGIILLAGFETSSAL 308
            ...:..|..:.|..|..|.....:|....:   :|..|..|.....:.::....:..|.:|:::.
Mouse   263 QVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASG 327

  Fly   309 MGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECT 373
            :.:..|.||..|:.|:|.|.|::......|:::::.|..:||..|...||||:||....|:||.:
Mouse   328 ISWIFYALATNPEHQQRCRKEIQSLLGDGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELS 392

  Fly   374 SSAS--EGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMTYIP 436
            |..:  :|.||        |.|:...:|..|||.:...||.|.||||.||.|..|||.|  :::|
Mouse   393 SPVTFPDGRSL--------PKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSSRHSH--SFLP 447

  Fly   437 FGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNP-------KSFMLESENEIYL 494
            |..|...|||.:..:.:||:.:...|.::          |:..:|       ...:|:|:|.|:|
Mouse   448 FSGGARNCIGKQFAMNELKVAVALTLLRF----------ELLPDPTRVPIPIPRIVLKSKNGIHL 502

  Fly   495  494
            Mouse   503  502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	99/455 (22%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	103/472 (22%)