Protein Alignment Cyp6t3 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 518
• Identity: 154/518 - (29%)
• Similarity: 248/518 - (47%)
• Gaps: 63/518 - (12%)

  Fly     5 WLLL-LTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLY---ADP 65
            |:|| :::|.|..:...|::.|:.:|||     ...|:..||.:|       :.::.|:   .:.
Mouse    12 WVLLAISLVLLYRYGTRKHELFKKQGIP-----GPKPLPFLGTVL-------NYYKGLWKFDMEC 64

  Fly    66 RNGQAKIVGFFIFQTPALMVRDPELIRQVLIKN-FNNFLNRFESADAGDPMGALT--LPLAKYHH 127
            .....|..|.|..|||.|.|.|||.|:.||:|. |:.|.||   .|.| |:|.::  :.::|...
Mouse    65 YKKYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNR---RDFG-PVGIMSKAISISKDDE 125

  Fly   128 WKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLYTTDVTGNL 192
            ||..|..:|..||||:::: |:..:......|.:||.:|.  :..:.:.:..:...|:.||..:.
Mouse   126 WKRYRALLSPTFTSGKLKE-MFPVIEQYGDILVKYLRQKA--KKGKPVTMKDVLGAYSMDVITST 187

  Fly   193 FYSLNVGGLRRGRSELITKTKELFNTNPRKVLDF-----MSVFFLPKWTGV---LKPKVFTEDYA 249
            .:.:||..|.......:.|.|:|..      .||     .||...|..|.|   |...:|.:|..
Mouse   188 SFGVNVDSLNNPEDPFVEKAKKLLR------FDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSI 246

  Fly   250 RYMRHLVDDHHEPTKGDLINQLQH----FQLSRSSNHYSQ----HPDF----VASQAGIILLAGF 302
            .:.:..||...|   ..|.::.:|    .||..:|::.|:    |...    :.:|:.|.:.||:
Mouse   247 EFFKKFVDRMKE---SRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGY 308

  Fly   303 ETSSALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAF 367
            ||:|:.:.|||:.||..||||::|:.|:.||..:.|..:|||:|.:.||.||..|.|||||.|..
Mouse   309 ETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANR 373

  Fly   368 VNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPM 432
            :.|.|.......       ...:|.|....|....||.|.:.|.||..|.||||..|....|.|.
Mouse   374 LERVCKKDVELN-------GVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPY 431

  Fly   433 TYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNPKSFMLESENEIYLR 495
            .|:|||.||..|:|.|..::.:||.:..|::.:..:.|:.|...::.: :..:|:.|..|.|:
Mouse   432 VYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLS-RQGLLQPEKPIVLK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	137/447 (31%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	138/449 (31%)