Protein Alignment Cyp6t3 and Cyp19a1

DIOPT Version :10

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031836.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 554
• Identity: 111/554 - (20%)
• Similarity: 212/554 - (38%)
• Gaps: 156/554 - (28%)

  Fly     1 MLLIWLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNL---GQLLFLRI-SFGDLFRQL 61
            :|||..|||.|          ::...|..||  .|.....:|.|   |:.|::.| |..:.:.::
Mouse    28 LLLIMGLLLLI----------WNCESSSSIP--GPGYCLGIGPLISHGRFLWMGIGSACNYYNKM 80

  Fly    62 YADPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDPMGALTLPLAKYH 126
            |.:       .:..:|.....|::.....:..|:  ..:::::||     |...|   |.....|
Mouse    81 YGE-------FMRVWISGEETLIISKSSSMFHVM--KHSHYISRF-----GSKRG---LQCIGMH 128

  Fly   127 H-----------WKESRQCMSQLFTS-GRMRDVMYSQMLDV-ASDLEQYLNRKLGDRLER----- 173
            .           |:..|....:..|. |.:|      |::| ...::|:|:| ||:..:.
Mouse   129 ENGIIFNNNPSLWRTIRPFFMKALTGPGLVR------MVEVCVESIKQHLDR-LGEVTDTSGYVD 186

  Fly   174 VLPLGRMCQLYTTDVTGNLFYSLNVGGLRRGRSELITKTKELFNTNPRKVLDFMSVFFLPKWTGV 238
            ||.|.|...|   |.:..||.     |:....|.::.|.:..||.                |..:
Mouse   187 VLTLMRHIML---DTSNMLFL-----GIPLDESAIVKKIQGYFNA----------------WQAL 227

  Fly   239 L-KPKVFTE------DYARYMRHLVDD--------HHEPTKGDLINQLQHFQLSRSSNHYSQHPD 288
            | ||.:|.:      .|.|.::.|.|:        .|:.:..:.:.....|.           .|
Mouse   228 LIKPNIFFKISWLYRKYERSVKDLKDEIAVLVEKKRHKVSTAEKLEDCMDFA-----------TD 281

  Fly   289 FV-ASQAGII------------LLAGFETSSALMGFTLYELAKAPDIQERLRSELREAFISTATL 340
            .: |.:.|.:            |:|..:|.|..:.|.|..:|:.|:::..:..|: ...:....:
Mouse   282 LIFAERRGDLTKENVNQCILEMLIAAPDTMSVTLYFMLLLVAEYPEVEAAILKEI-HTVVGDRDI 345

  Fly   341 SYDTLMTLPYLKMVCLEALRLYPAAAFV-NRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLH 404
            ..:.:..|..::....|::|..|....| .|.......:|:.::...:.|        ::|..:|
Mouse   346 KIEDIQNLKVVENFINESMRYQPVVDLVMRRALEDDVIDGYPVKKGTNII--------LNIGRMH 402

  Fly   405 RDERFWPEPCVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVET 469
            |.| ::|:|..|..|.|    .:::....:.|||.||.||.|..:.::.:|:.:|.:|:::.|:|
Mouse   403 RLE-YFPKPNEFTLENF----EKNVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKT 462

  Fly   470 ----C----------------ERTVSEIRFNPKS 483
                |                :|.:.||.|:|::
Mouse   463 LQKRCIENIPKKNDLSLHPNEDRHLVEIIFSPRN 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	93/483 (19%)
Cyp19a1	NP_031836.1	CYP19A1	72..485	CDD:410709	90/485 (19%)