Protein Alignment Cyp6t3 and CYP4F8

DIOPT Version :9

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 132/553 - (23%)
• Similarity: 225/553 - (40%)
• Gaps: 118/553 - (21%)

  Fly     5 WLLLLTIVTLNFWLRHK-----YDYF----RSRGIPHLPPSSWSPMGNLGQLL----FLRISFGD 56
            |||||.:..  .||..:     |.::    |.|..|.....:|. :|:||.:.    .||:
Human    19 WLLLLVVGA--SWLLARILAWTYAFYHNGRRLRCFPQPRKQNWF-LGHLGLVTPTEEGLRV---- 76

  Fly    57 LFRQLYADPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADA---------- 111
             ..||.|....|..:.:|..   ||.:.:..|:::|.|:           .::||
Human    77 -LTQLVATYPQGFVRWLGPI---TPIINLCHPDIVRSVI-----------NTSDAITDKDIVFYK 126

  Fly   112 ------GDPMGALTLPLAKYHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDR 170
                  ||  |.|   |:....|:..|:.::..|....::.  |.::...::::       :..:
Human   127 TLKPWLGD--GLL---LSVGDKWRHHRRLLTPAFHFNILKP--YIKIFSKSANI-------MHAK 177

  Fly   171 LERVLPLGRMC-------QLYTTDVTGNLFYSLNVGGLRRGRSELITKTKELF------NTNPRK 222
            .:|:...|..|       .|.|.|......:|.: ...:...||.||...||.      |....:
Human   178 WQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFD-SNCQEKPSEYITAIMELSALVVKRNNQFFR 241

  Fly   223 VLDFMSVFFLPKWTGVLKP------------KVFTEDYARYMRHL-----VDDH-HEPTKGDLIN 269
            ..||:  :|       |.|            ..||:...:..|..     |||. ....|...::
Human   242 YKDFL--YF-------LTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLD 297

  Fly   270 QLQHFQLSRSSNHYSQHPDFVASQAGIILLAGFETSSALMGFTLYELAKAPDIQERLRSELREAF 334
            .:....||...|......:.:.::|...:..|.:|:::.:.:.||.||:.|:.|||.|.|::|..
Human   298 FIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362

  Fly   335 --ISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAY 397
              .....:.:|.|..||:|.|...|:|||:|......|.||...     :.|. ..::|.|....
Human   363 KDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDV-----VLPD-SRVIPKGNVCN 421

  Fly   398 ISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHIL 462
            |:|..:|.:...||:|.|:||.||.||.::...||.:|||.|||..|||.:..:.::|:.:...|
Human   422 INIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTL 486

  Fly   463 KQYWVETCERTVSEIRFNPKSFMLESENEIYLR 495
            .::.:....|   |.|..|: .:|.:|:.::||
Human   487 LRFRILPDHR---EPRRTPE-IVLRAEDGLWLR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	117/504 (23%)
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	118/505 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920