Protein Alignment Cyp6g2 and ERG11

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 127/518 - (24%)
• Similarity: 206/518 - (39%)
• Gaps: 118/518 - (22%)

  Fly     5 LLILVASLIGIAFLALQQHYSYWRRMGVREIRPK----WI--VGN--LMGLLNMRMSPAEFISQL 61
            |:|::..:..|.:..|   ||      :|:.||.    ||  ||:  :.|     |.|.||..:.
Yeast    33 LIIIIPFIYNIVWQLL---YS------LRKDRPPLVFYWIPWVGSAVVYG-----MKPYEFFEEC 83

  Fly    62 Y-NHPDAENEPFVG--IHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDPLGSQNIFF 123
            . .:.|..:...:|  :.|:..|    :..|.|.|..:.|.:..:.....:.|   ..|...|:.
Yeast    84 QKKYGDIFSFVLLGRVMTVYLGP----KGHEFVFNAKLADVSAEAAYAHLTTP---VFGKGVIYD 141

  Fly   124 LKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLH--NERMRCFDLEAKELCAL 186
            ..|....|.:..:....|....|...|||.|   .:..:.|.....  |||
Yeast   142 CPNSRLMEQKKFVKGALTKEAFKSYVPLIAE---EVYKYFRDSKNFRLNER-------------- 189

  Fly   187 YTTDVIATVAYGVSANSFTDPKCEFRRHGRSVF--EFNLLRAAEFTLVF------FLPHLVPFVR 243
             ||..|..:.        |.|:.......||:.  |.......:|..::      |.|  :.||
Yeast   190 -TTGTIDVMV--------TQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTP--INFV- 242

  Fly   244 FKVVPAE-------ATRFLRKTINYVMSEREKSGQ-KRNDLIDILIEFRRSTQLAKASGIK--DQ 298
            |..:|.|       |.:.:..|...::.||.|:.. :..||||.|:  :.||.   ..|:|  ||
Yeast   243 FPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLM--KNSTY---KDGVKMTDQ 302

  Fly   299 FVFEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIE 363
            .:  .::|:  .||.  .|..:|::|.|:.:..||:..||||.|.||....|.....::|..:::
Yeast   303 EI--ANLLI--GVLM--GGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQ 361

  Fly   364 SLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYI-PCYALHMDPQYFP 427
            .:..:...:.|.|||:.||..|.|:..  :|..:.  :..:|:|.|..|.: |.|. |:..:|||
Yeast   362 EMPLLNQTIKETLRMHHPLHSLFRKVM--KDMHVP--NTSYVIPAGYHVLVSPGYT-HLRDEYFP 421

  Fly   428 QPRKFLPERFSPE------------------NRKLHTPYTYMPFGLGPHGCIGERFGYLQAKV 472
            ...:|...|::.:                  ::.:.:|  |:|||.|.|.||||.|.|.|..|
Yeast   422 NAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSP--YLPFGGGRHRCIGEHFAYCQLGV 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	108/445 (24%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	109/454 (24%)