Protein Alignment Cyp6g2 and ERG5

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 546
• Identity: 123/546 - (22%)
• Similarity: 217/546 - (39%)
• Gaps: 128/546 - (23%)

  Fly     3 LVLLILV----------ASLIGIAFLALQQHYSYWRRMG---------VREIRPKWIVGNLMGLL 48
            |:.::||          .|:.|..|       .:|..:|         ..|.:.||..|
Yeast    52 LICILLVWDQVAYQIKKGSIAGPKF-------KFWPIIGPFLESLDPKFEEYKAKWASG------ 103

  Fly    49 NMRMSPAEFISQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSS---D 110
                                  |...:.:|||..::....::.|.||.      |:::...   |
Yeast   104 ----------------------PLSCVSIFHKFVVIASTRDLARKILQ------SSKFVKPCVVD 140

  Fly   111 PKGDPLGSQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEV-GASLDAHLRQQPLHNERMR 174
            .....|...|..||...|..:.|..|:..||...|.|..|.:|:: ...:|..:|....:|...:
Yeast   141 VAVKILRPCNWVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQ 205

  Fly   175 CFDLEAKE-LCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAA-EFTLVFFLPH 237
            .|..|.:| ||||             |.|||    |     |..:.|..:.:.| ::.||.....
Yeast   206 VFFHEMREILCAL-------------SLNSF----C-----GNYITEDQVRKIADDYYLVTAALE 248

  Fly   238 LVPFVRFKVVPAEATRFLRKTINYVMSEREKSGQKRNDLID-------ILIEFRRSTQLAKASGI 295
            ||.|.  .::|...|.:.:||.:..|...|...|...|.|.       ::..:.:....||.|..
Yeast   249 LVNFP--IIIPYTKTWYGKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSND 311

  Fly   296 KDQFVFEGDIL---VAQAVLFFTAGFESSSSTMAFAMYELAKD-TDVQQRLREE---IKDALVES 353
            .|..::..:..   :::||..|....:.:||::|..::::..| .||..::|||   :::.  :.
Yeast   312 DDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNN--DM 374

  Fly   354 GGQVTLKMIESLEFMQMILLEVLRMYPP---LPFLDRECTSGRDYSLAPFHKKFVVPKG---MPV 412
            ..::.|.:||.:::..|::.|.||..||   :|::.:     :::.::|   .:..|||   :|.
Yeast   375 STELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVK-----KNFPVSP---NYTAPKGAMLIPT 431

  Fly   413 YIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGE-----RFGYLQAKV 472
            ..|  ||| ||:.:..|.:|:|||:...::.......::.||.|||.|:|:     .|..|..|.
Yeast   432 LYP--ALH-DPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKF 493

  Fly   473 GLVNLLRNHMITTSERTPHRMQLDPK 498
            .|.....:.:...||:......:.||
Yeast   494 ALYTDFHHTVTPLSEKIKVFATIFPK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	111/461 (24%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	112/488 (23%)