Protein Alignment Cyp6g2 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 532
• Identity: 158/532 - (29%)
• Similarity: 276/532 - (51%)
• Gaps: 52/532 - (9%)

  Fly     1 MELV-------LLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFI 58
            |||:       .::||.||:.........| ..::::|:...:|..::|.:....:......|..
Mouse     1 MELIPNLSIETWVLLVTSLVLFYIYGTYSH-GLFKKLGIPGPKPLPLLGTIFNYYDGMWKFDEDC 64

  Fly    59 SQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKD-FAGFSNRYSSSDPKGDPLG--SQN 120
            .:.|.       ...|.:...:|.|.:.|||:::.:|||: ::.|:||....     |:|  .:.
Mouse    65 YKKYG-------KIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFG-----PVGFMKKA 117

  Fly   121 IFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCA 185
            |...::..||.:|..|||.||..:||:|||::.:.|..|..:||::....|     .:..|::..
Mouse   118 ITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGE-----PISMKDIFG 177

  Fly   186 LYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVP---FVRFKVV 247
            .|:.|||...::||:.:|..:|:..|.:..:.:.:|.:......:::.| |.|.|   .:.|.:.
Mouse   178 AYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILF-PFLTPIYEMLNFSIF 241

  Fly   248 PAEATRFLRKTINYVMSEREKSGQK-RNDLIDILIEFRRSTQLAKASGIKDQFVFEGDILVAQAV 311
            |.::..|.:|.:..:..||..|.|| |.|.:.:::    :||.:|  |.:.|.......:.||||
Mouse   242 PRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMM----NTQNSK--GQESQKALSDLEMAAQAV 300

  Fly   312 LFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIESLEFMQMILLEVL 376
            :|...|::::|::::..|||||...|||::|::|| |..:.:...||...:..:|::.|::.|.|
Mouse   301 IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEI-DRTLPNKAPVTYDALMDMEYLDMVVNESL 364

  Fly   377 RMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPEN 441
            |:||....|:|  .|.:|..:    ....:|||..|.||.|.||.:|:|:|:|::|.|||||.||
Mouse   365 RLYPIAIRLER--VSKKDVEI----NGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKEN 423

  Fly   442 RKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERT--PHRMQLDPKAIITQA 504
            :....||.|||||.||..|||.||..:..|:.::.:|:|..:...|.|  |.::..:|   |.|.
Mouse   424 KGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREP---IFQP 485

  Fly   505 KGGIHLRLV-RD 515
            :..|.|::| ||
Mouse   486 EKPIILKVVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	140/448 (31%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	142/458 (31%)