Protein Alignment Cyp6g2 and CYP26C1

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_899230.2
• Gene: CYP26C1 / 340665
• HGNCID: 20577
• Length: 522
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 100/451 - (22%)
• Similarity: 163/451 - (36%)
• Gaps: 106/451 - (23%)

  Fly    76 HVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDP--LGSQNIFFLKNPAWKEVRLKLSP 138
            |:..:|.:.:...|.||.||:    |......|..|:...  |||..:........:..|..|:.
Human    87 HLLGRPVIRVSGAENVRTILL----GEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLAR 147

  Fly   139 FFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALYTTDVIATVAYGVSANS 203
            .|:...|::..|.::  ||     ||    |..|..|                    |.|...:.
Human   148 VFSRAALERYVPRLQ--GA-----LR----HEVRSWC--------------------AAGGPVSV 181

  Fly   204 FTDPKC-EFRRHGRSVFEFNLLRAAEFTL----------VFFLPHLVPFVRFKVVPAEATRFLRK 257
            :...|. .||...|.:....|..|...||          :|.||..|||...: ....|...|.:
Human   182 YDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLR-KGIRARDQLHR 245

  Fly   258 TINYVMSER--EKSGQKRNDLIDILIEFRR------STQLAKASGIKDQFVFEGDILVAQAVLFF 314
            .:...:||:  |....:..|.:|::|...|      |.|..|.|.::               |.|
Human   246 HLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVE---------------LLF 295

  Fly   315 TAGFESSSSTMAFAMYELAKDTDVQQRLREEIKD---------ALVESGG------------QVT 358
            .|.|.::|::.:..:..|.....: .::|||:..         |...:||            .::
Human   296 AAFFTTASASTSLVLLLLQHPAAI-AKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLS 359

  Fly   359 LKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFH-KKFVVPKGMPVYIPCYALHMD 422
            |..:..|.::..::.||||:.||:       :.|...:|..|. ..:.:|||..|.......|..
Human   360 LAALGRLRYVDCVVKEVLRLLPPV-------SGGYRTALRTFELDGYQIPKGWSVMYSIRDTHET 417

  Fly   423 PQ-YFPQPRKFLPERFS---PENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLR 479
            .. |...|..|.||||.   .::|...:.:.|:|||.|...|:|:.......::..|.|:|
Human   418 AAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVR 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	100/451 (22%)
CYP26C1	NP_899230.2	CYP26C1	59..508	CDD:410729	100/451 (22%)