Protein Alignment Cyp6g2 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 155/496 - (31%)
• Similarity: 245/496 - (49%)
• Gaps: 72/496 - (14%)

  Fly    54 PAEFISQLYNHPDAENEPFVGIHVF----HK-------------PALLLRDPEMVRNILVKD-FA 100
            |..|...:.|:       ::|:..|    ||             |...:.|.||::|:|||: |:
  Rat    43 PLPFFGTVLNY-------YMGLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFS 100

  Fly   101 GFSNRYSSSDPKGDPLG--SQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHL 163
            .|:||....     |:|  .:.|...|:..||..|..|||.||..|||:|||:||:.|..|..:|
  Rat   101 VFTNRRDFG-----PVGIMGKAISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYL 160

  Fly   164 RQQPLHNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAE 228
            ||:       :...:..||:...|:.|||.:.::||:.:|..:||..|....:.:...:......
  Rat   161 RQE-------KGKPVPVKEVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLF 218

  Fly   229 FTLVFFLPHLVP---FVRFKVVPAEATRFLRKTINYVMSEREKSGQK-RNDLIDILIEFRRSTQL 289
            .::|.| |.|.|   .:...:.|.::..|.:|.:..:...|..|.|| |.|.:.:::.....
  Rat   219 LSVVLF-PFLTPVYEMLNICMFPKDSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHND--- 279

  Fly   290 AKASGIKDQFVFEGDI-LVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVES 353
               |..|:......|: :.||:::|..||:|.:|||::|.::.||...|.|::|:||| |..:.:
  Rat   280 ---SKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEI-DRALPN 340

  Fly   354 GGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKFV------VPKGMPV 412
            ....|...:..:|::.|:|.|.||:||....|:|.|            ||.|      :|||..|
  Rat   341 KAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVC------------KKDVEINGVFMPKGSVV 393

  Fly   413 YIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNL 477
            .||.||||.|||::|:|.:|.|||||.||:....||.|:|||.||..|||.||..:..|:.|..:
  Rat   394 MIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKV 458

  Fly   478 LRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLV-RDAL 517
            |:|......:.|...::|..:.::...| .|.|::| ||.:
  Rat   459 LQNFSFQPCKETQIPLKLSRQGLLQPTK-PIILKVVPRDEI 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	147/470 (31%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	144/456 (32%)