Protein Alignment Cyp6g2 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 155/529 - (29%)
• Similarity: 275/529 - (51%)
• Gaps: 64/529 - (12%)

  Fly     7 ILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFISQLYNHPDA---- 67
            :|:|:.:.:.::.....:..::::|:.  .||               |......::|:.|.
  Rat    13 VLLATSLMLFYIYGTYSHGLFKKLGIP--GPK---------------PVPLFGTIFNYGDGMWKF 60

  Fly    68 ENEPFV------GIHVFHKPALLLRDPEMVRNILVKD-FAGFSNRYSSSDPKGDPLG--SQNIFF 123
            :::.:.      |.:...:|.|.:.|||:::.:|||: ::.|:||....     |:|  .:.|..
  Rat    61 DDDCYKKYGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFG-----PMGFMKKAITM 120

  Fly   124 LKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALYT 188
            .::..||.:|..|||.||..:||:||||:.:.|.:|..:||::....|     .:..|::...|:
  Rat   121 SEDEEWKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGE-----PINMKDIFGAYS 180

  Fly   189 TDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVP---FVRFKVVPAE 250
            .|||...::||:.:|..:|:..|.:..:.:.:|.:......::|.| |.|.|   .:.|.:.|.:
  Rat   181 MDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLF-PFLTPIYEMLNFSIFPRQ 244

  Fly   251 ATRFLRKTINYVMSEREKSGQK-RNDLIDILIEFRRSTQLAKASGIKDQFVFEGDILVAQAVLFF 314
            :..|.:|.:..:...|..|.|| |.|.:.:::    :||.:|  |.:.|.......:.|||::|.
  Rat   245 SMNFFKKFVKTMKKNRLDSNQKSRVDFLQLMM----NTQNSK--GQESQKALSDLEMAAQAIIFI 303

  Fly   315 TAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIESLEFMQMILLEVLRMY 379
            ..|::::|::::|.|||||...:||::|:.|| |..:.:...||...:..:|::.|::.|.||:|
  Rat   304 FGGYDATSTSISFIMYELATRPNVQKKLQNEI-DRALPNKAPVTYDALMEMEYLDMVVNESLRLY 367

  Fly   380 PPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKL 444
            |....|||  .|.:|..:    ....:|||..|.||.|.||.:|:|:.:|.:|.|||||.||:..
  Rat   368 PIATRLDR--VSKKDVEI----NGVFIPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGS 426

  Fly   445 HTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERT--PHRMQLDPKAIITQAKGG 507
            ..||.|:|||.||..|||.||..:..|:.::.:|:|..|...|:|  |.::...|   |.|.:|.
  Rat   427 IDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKTQIPLKISRQP---IFQPEGP 488

  Fly   508 IHLRLV-RD 515
            |.|:|| ||
  Rat   489 IILKLVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	141/454 (31%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	142/451 (31%)