Protein Alignment Cyp6g2 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 129/559 - (23%)
• Similarity: 237/559 - (42%)
• Gaps: 113/559 - (20%)

  Fly     5 LLILVASLIG---IAFLALQQHYSYWRRMGVREIRPK---------WIVGNLMGLLNMRMSPAEF 57
            :.||:.|.|.   |.|::    ||.|||..:.::|..         |:.||| .::..|:|...:
 Worm     1 MAILIISTIFFTIITFIS----YSIWRRHAIFKLRSSIGIPGPPVHWLWGNL-NIIKDRVSRLGY 60

  Fly    58 ISQLYNHPDAENE--PFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDPLGSQN 120
            ......||....:  |..|::...:..:.:.:.|.::.|.:::|:.||:|.:   |....:...|
 Worm    61 NDTTQWHPTLHTKYGPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMT---PDIFGMNQLN 122

  Fly   121 IFFLKN---PAWKEVRLKLSPFFTGNRLKQMF-PLIEEVGASLDAHLRQQPLHNERMRCFD-LEA 180
            ...|:|   ..||..|..::|.|:..::|.|. .|:.::...|:. |:::....::...|: .::
 Worm   123 QSLLQNTYATGWKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEV-LKEKSSSGQKWDIFENFQS 186

  Fly   181 KELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRS---------------------------- 217
            ..|      |:|...|:.:.:|...|....|....|.
 Worm   187 LSL------DIIGKCAFAIDSNCQRDRTDLFYVQARKFVGAVDLKKSWILPVSLILPELSWLWRF 245

  Fly   218 VFEFNLLRAAEFTLVFFLPHLVPFVRFKVVPAEATRFLRKTINYVMSEREKSGQKRNDLIDIL-I 281
            :::|:.|.|||..||..|..|.                         :|.::|:..||..|:| :
 Worm   246 LYKFSDLSAAELPLVKGLVDLY-------------------------DRRRAGEGGNDSTDLLNL 285

  Fly   282 EFRRST--QLAKASGIKDQFVFEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLRE 344
            ..||.|  ::.:...|::.|.            |..||:|::|:.|.|:.|.||:...|||:|.|
 Worm   286 LIRRETIGKMTQREVIENCFA------------FLIAGYETTSTAMMFSAYLLAEYPIVQQKLYE 338

  Fly   345 EIKDALVESGGQVTLKMIESLEFMQMILLEVLRMYPPLP-FLDRECTSGRDYSLAPFHKKFVVPK 408
            |||.....:|  :....|.:::::..:..|.||.|||.. |.:|.|.:  |.::    :..:.|:
 Worm   339 EIKKTKENAG--LNYDSIHNMKYLDCVYKESLRFYPPTTHFTNRVCLN--DMTI----RGQIYPE 395

  Fly   409 GMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVG 473
            ...:.:..|.:|.:|..:..|.:|.||||.....| .:...::|||:||..|:|.||..::.|..
 Worm   396 DSTLKVQPYTIHRNPANWESPDEFQPERFENWEEK-SSSLKWIPFGVGPRYCVGMRFAEMEFKTT 459

  Fly   474 LVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRL 512
            :..||....::.....| .|..:...:|.:.:..:.|.|
 Worm   460 IAKLLDTFELSLVPGDP-PMIPETNGVIFRPRSPVRLNL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	107/478 (22%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	107/477 (22%)