Protein Alignment Cyp6g2 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 149/508 - (29%)
• Similarity: 262/508 - (51%)
• Gaps: 41/508 - (8%)

  Fly     6 LILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFISQLYNHPDAENE 70
            |:||.||: :.:|.....:..::::|:...:|...:|.   :|..|....||  ..|.|  .:..
  Rat    13 LLLVISLV-LLYLYGTHSHGIFKKLGIPGPKPLPFLGT---ILAYRKGFWEF--DKYCH--KKYG 69

  Fly    71 PFVGIHVFHKPALLLRDPEMVRNILVKD-FAGFSNRYSSSDPKGDPLG--SQNIFFLKNPAWKEV 132
            ...|::...:|.|.:.||::::.:|||: ::.|:||.:..     |:|  .:.|...::..||.:
  Rat    70 KLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFG-----PVGILKKAISISEDEEWKRI 129

  Fly   133 RLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALYTTDVIATVAY 197
            |..|||.||..:||:|||:|.:....|..::||.....:     ....|::...|:.|||...::
  Rat   130 RALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGK-----PTSMKDIFGAYSMDVITATSF 189

  Fly   198 GVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVPF---VRFKVVPAEATRFLRKTI 259
            ||:.:|..:|:..|....:.:.:|::.... |..|...|.|.|.   :...:.|.:...|.:.::
  Rat   190 GVNVDSLNNPQDPFVEKIKKLLKFDIFDPL-FLSVTLFPFLTPLFEALNVSMFPRDVIDFFKTSV 253

  Fly   260 NYVMSEREKSGQK-RNDLIDILIEFRRSTQLAKASGIKDQFVFEGDI-LVAQAVLFFTAGFESSS 322
            ..:...|.|..:| |.|.:.::|.       ::.|.:||......|: :|||:|:|..||:|::|
  Rat   254 ERMKENRMKEKEKQRMDFLQLMIN-------SQNSKVKDSHKALSDVEIVAQSVIFIFAGYETTS 311

  Fly   323 STMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDR 387
            |.::|.:|.||...|:|::|::|| ||.:.:....|...:..:|::.|::.|.||:||....|:|
  Rat   312 SALSFVLYLLAIHPDIQKKLQDEI-DAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLER 375

  Fly   388 ECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMP 452
            .|.:..:.:      ...:|||..|.||.:|||.||.|:|:|.:|.|||||.:|:....||.|:|
  Rat   376 VCKTDVEIN------GVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLP 434

  Fly   453 FGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAK 505
            ||.||..|||.||..:..||.||.:|:|......:.|...::|..:.::...|
  Rat   435 FGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKLSKQGLLQPEK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	134/445 (30%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	134/446 (30%)