Protein Alignment Cyp6g2 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_610744.1
• Gene: Cyp6g2 / 36317
• FlyBaseID: FBgn0033696
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 524
• Identity: 160/524 - (30%)
• Similarity: 273/524 - (52%)
• Gaps: 49/524 - (9%)

  Fly     7 ILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLM----GLLNMRMSPAEFISQLYNHPDA 67
            :|:|.::.:.:....:.:..:::.|:...:|...:|.::    ||....|...|...:.:
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYEKYGKTW----- 72

  Fly    68 ENEPFVGIHVFHKPALLLRDPEMVRNILVKD-FAGFSNRYSSSDPKGDPLG--SQNIFFLKNPAW 129
                  |:.....|..::.||||::|:|||: |:.|:||....     |:|  |:.|...|:..|
Mouse    73 ------GLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFG-----PVGIMSKAISISKDEEW 126

  Fly   130 KEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALYTTDVIAT 194
            |..|..|||.||..:||:|||:||:.|..|..:|.|     |..:...:..|::...|:.|||.:
Mouse   127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQ-----EAEKGKPVTMKDVLGAYSIDVITS 186

  Fly   195 VAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVP---FVRFKVVPAEATRFLR 256
            .::||:.:|..:|:..|....:.:...:......|::|.| |.|.|   .:...:.|.::..|.:
Mouse   187 TSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLF-PFLTPVYEMLNICMFPKDSIEFFK 250

  Fly   257 KTINYVMSEREKSGQK-RNDLIDILIEFRRSTQLAKASGIKDQFVFEGDI-LVAQAVLFFTAGFE 319
            |.:|.:...|..|.|| |.|.:.:::....:      |..||......|: :.||:::|..||:|
Mouse   251 KFVNRMKESRLDSKQKHRVDFLQLMMNAHNN------SKDKDSHKALSDMEITAQSIVFIFAGYE 309

  Fly   320 SSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIESLEFMQMILLEVLRMYPPLPF 384
            ::|||::|.:|.||...|:|::|:||| |..:.:....|...:..:|::.|:|.|.||:||....
Mouse   310 TTSSTLSFTLYCLATHPDIQKKLQEEI-DETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNR 373

  Fly   385 LDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYT 449
            |:|.|.  :|..|...:    :|||..|.||.||||.|||::|:|.:|.|||||.||:....||.
Mouse   374 LERFCK--KDVELNGVY----IPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYL 432

  Fly   450 YMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLV- 513
            |||||:||..|||.||.::..|:.|..:::|......:.|...::|..:.:: |.:..|.|::|
Mouse   433 YMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLL-QPEKPIVLKVVP 496

  Fly   514 RDAL 517
            ||.:
Mouse   497 RDVV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g2	NP_610744.1	CYP6-like	69..509	CDD:410679	146/447 (33%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	147/461 (32%)