Protein Alignment Cyp6g1 and ERG11

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 478
• Identity: 108/478 - (22%)
• Similarity: 181/478 - (37%)
• Gaps: 105/478 - (21%)

  Fly    76 IYSMNK--PGLIIRDIELIKSILI---KDFNRFHNRYARCD-PHGD----------------PLG 118
            :||:.|  |.|:...|..:.|.::   |.:..|.    .|. .:||                |.|
Yeast    48 LYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFE----ECQKKYGDIFSFVLLGRVMTVYLGPKG 108

  Fly   119 YNNLFFVRDAHWKGIRTK------LTPVFTSGKVKQM-YTLMQEIGKDLELALQRRGEKNSGSFI 176
            :.   ||.:|....:..:      .||||..|.:... .:.:.|..|.::.||.:...|   |::
Yeast   109 HE---FVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFK---SYV 167

  Fly   177 TEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARA-----------KDF-F 229
            ..|.|...::..||     ...|.|.......:......:|..||.:|:           .|| :
Yeast   168 PLIAEEVYKYFRDS-----KNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAY 227

  Fly   230 VAFFLPKLVSLMRIQFFTADFSHFMR----------STIGHVMEERERSGLLRNDLIDVLVSLRK 284
            :...|.|..:.:...|......|:.:          :.:..:.|.|:.:.:...||||   ||.|
Yeast   228 LYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLID---SLMK 289

  Fly   285 EAAAEPSKPHYAKNQDFLVAQ--AGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALV 347
            .:..:..    .|..|..:|.  .||.. .|..||::|.::.|..:|:.|::|:.|.:|....|.
Yeast   290 NSTYKDG----VKMTDQEIANLLIGVLM-GGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLD 349

  Fly   348 EGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFI 412
            .|...|:|:.:|.:..|...:.|.|||:..|..|.|:.......|:.|      |.:..|..|.:
Yeast   350 GGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTS------YVIPAGYHVLV 408

  Fly   413 PIYALHHDPKYWTNPSQFDPERFSPANRKNI----------------VAMAYQPFGSGPHNCIGS 461
            .....|...:|:.|..||:..|::..:..:.                |:..|.|||.|.|.|||.
Yeast   409 SPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGE 473

  Fly   462 -----RIGLLQSKLGLVSLLKNH 479
                 ::|:|.|.  .:..||.|
Yeast   474 HFAYCQLGVLMSI--FIRTLKWH 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	108/478 (23%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	99/439 (23%)