DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6g1 and CYP96A8

DIOPT Version :9

Sequence 1:	NP_001286335.1	Gene:	Cyp6g1 / 36316	FlyBaseID:	FBgn0025454	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_175193.1	Gene:	CYP96A8 / 841171	AraportID:	AT1G47620	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	582	Identity:	124/582 - (21%)
Similarity:	206/582 - (35%)	Gaps:	157/582 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LTEVLFVVVAALVALYTWFQRNHSY-----------WQRKGIPYIP------------PTPIIGN 44
            |.|.....:..|::.|...::..||           |....:..:|            ...::.|
plant     6 LYEAFIGFLCFLISFYFLVKKPFSYLLIKKTLQSYPWNWPVLGMLPGVLLRLQRIYDCSVEVLEN 70

  Fly    45 TKVVFKMENSF--GM------------HLSEIYNDPRLKDEAVVGIYSMNKPGLIIRDIELIK-- 93
            :.:.|:.:..:  ||            |:........:|......|:.....|:|..|.||.:
plant    71 SNMTFQFKGPWFVGMDVLATVDPANIHHIMSSNFSNYIKGPIFHEIFEAFGDGIINTDAELWRDW 135

  Fly    94 ---SILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQE 155
               |.||  ||  |.||..              |........:...|.|:|.       :...:|
plant   136 RNASQLI--FN--HQRYQN--------------FSASTTKTKVNDGLVPLFN-------HFANEE 175

  Fly   156 IGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTF 220
            |..|||...||.....:..|||         .||.        |:.|:|.|..||
plant   176 IVVDLEDVFQRFMYDITFIFIT---------GTDP--------RSLSIEMPEVEF---------- 213

  Fly   221 TVARAKD-----FFVAFFLPKLVSLMRIQFFT------------ADFSHFMRSTIGHVMEERERS 268
              ::|.|     .......|:.|  .::|.:.            |.|.......|....||....
plant   214 --SKALDDVGDAIVHRHITPRFV--WKLQKWIGIGTEKKMLKAHATFDRVCEKIIAAKREELGSQ 274

  Fly   269 GLLRN---DLIDVLVSLRKEAAA--EPSKPHYAK-NQDFLVAQAGVFFTAGFETSSSTMSFALYE 327
            |:..|   :..|:|.|..|..|.  |..||.:.| .:||.:.    |..||.::::||:::..:.
plant   275 GITYNSNGEREDLLTSFIKLDATKYEVLKPSHDKFLRDFTIG----FMAAGRDSTASTLTWFFWN 335

  Fly   328 MAKHPEMQKRLRDEINEALVEGGGS---LSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVE 389
            ::|:|.:..::..|||..|...|..   .||  :..|.||...:.|.:|:||.:||..:
plant   336 LSKNPNVLTKILQEINTNLPRTGSDQDMSSY--LNKLVYLHGALSESMRLYPPIPFQRK------ 392

  Fly   390 GQPDLSLKPFYDYTLENGTPV------FIPIYALHHDPKYW-TNPSQFDPERF--SPANRKNIVA 445
                   .|..:..|.:|..|      .|.|||:......| .:..:|.|||:  .....::..:
plant   393 -------SPIKEDVLPSGHKVKSNINIMIFIYAMGRMKTIWGEDAMEFKPERWISETGGVRHEPS 450

  Fly   446 MAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPK-GFVLQADGGI 506
            ..:..|.:||..|:|..:.:...|..:|.:|:|:.::    .:...|.:|| |.:|....|:
plant   451 YKFLSFNAGPRTCLGKNLAMNLMKTVIVEILQNYEIK----IVSGQKIEPKPGLILHMKHGL 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_001286335.1	p450	56..508	CDD:278495	114/504 (23%)
CYP96A8	NP_175193.1	p450	1..515	CDD:386267	124/582 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000