DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6g1 and CYP711A1

DIOPT Version :9

Sequence 1:	NP_001286335.1	Gene:	Cyp6g1 / 36316	FlyBaseID:	FBgn0025454	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_565617.2	Gene:	CYP711A1 / 817157	AraportID:	AT2G26170	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	133/559 - (23%)
Similarity:	217/559 - (38%)	Gaps:	114/559 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLKD 70
            :.|:..||:|.:...::.:   |....:|.....|::|:..::.|    :|..:..:.    .|.
plant    22 IAFLTFAAVVIVIYLYRPS---WSVCNVPGPTAMPLVGHLPLMAK----YGPDVFSVL----AKQ 75

  Fly    71 EAVVGIYSMNK-PGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGIR 134
            ...:..:.|.: |.:||.:.||.:.:.||.|....||.........||....|||.||..|..:|
plant    76 YGPIFRFQMGRQPLIIIAEAELCREVGIKKFKDLPNRSIPSPISASPLHKKGLFFTRDKRWSKMR 140

  Fly   135 TKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITE-------------IKEICAQF 186
            ..:..::....:..:...|.                   ||||.             ...:..:.
plant   141 NTILSLYQPSHLTSLIPTMH-------------------SFITSATHNLDSKPRDIVFSNLFLKL 186

  Fly   187 STDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLV------------S 239
            :||.|...|||:          :|...|:|..       ||..|..|:.:.|            |
plant   187 TTDIIGQAAFGV----------DFGLSGKKPI-------KDVEVTDFINQHVYSTTQLKMDLSGS 234

  Fly   240 L-----MRIQFFTADFSHFMRSTIGHVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPH----- 294
            |     :.|......|...::...|.:....|::....:..::.:||.|.:.|...||..
plant   235 LSIILGLLIPILQEPFRQVLKRIPGTMDWRVEKTNARLSGQLNEIVSKRAKEAETDSKDFLSLIL 299

  Fly   295 -------YAKN---QDFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEI----NEA 345
                   :|||   .|::.|.......||..|::.|:|..||.::.|.:::|||..||    |..
plant   300 KARESDPFAKNIFTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRLLQEIDGFGNRD 364

  Fly   346 LVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDRE-YESVEGQPDLSLKPFYDYTLENGTP 409
            |:.....|.::    ..||..|:.|.:|.|.|.|.:.|| .:.||         ...|.|..||.
plant   365 LIPTAHDLQHK----FPYLDQVIKEAMRFYMVSPLVARETAKEVE---------IGGYLLPKGTW 416

  Fly   410 VFIPIYALHHDPKYWTNPSQFDPERFSP--ANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGL 472
            |::.:..|..|||.:..|.:|.||||.|  ...|:....|:.|||.||..|:|.|..|.:.||.|
plant   417 VWLALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQRFALQEIKLTL 481

  Fly   473 VSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIV 511
            :.|.:|:..|:.......::.| .|.:|....|:.|..:
plant   482 LHLYRNYIFRHSLEMEIPLQLD-YGIILSFKNGVKLRTI 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_001286335.1	p450	56..508	CDD:278495	123/504 (24%)
CYP711A1	NP_565617.2	cytochrome_P450	75..515	CDD:425388	121/489 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786853at2759
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.860