Protein Alignment Cyp6g1 and TBXAS1

DIOPT Version :9

• Sequence 1: NP_001286335.1
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001159725.2
• Gene: TBXAS1 / 6916
• HGNCID: 11609
• Length: 579
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 153/609 - (25%)
• Similarity: 260/609 - (42%)
• Gaps: 148/609 - (24%)

  Fly     6 VLFVVVAALVALYTWFQRN-HSYWQRKGIPYIPPTPIIGNTKVVFKMENSF--GMHLSEIYNDPR 67
            |...:..||:||..|:..: .|..::.|:.:..|:|.|||  :.|..:..:  .|.|.::|.
Human    16 VTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGN--LTFFRQGFWESQMELRKLYG--- 75

  Fly    68 LKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGY----NNLFFVRDA 128
                .:.|.|...:..::|.:.::||.:|:::|:.|.||.|      ..|.:    :::.|:||.
Human    76 ----PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMA------SGLEFKSVADSVLFLRDK 130

  Fly   129 HWKGIRTKLTPVFTSGKVKQM-YTLMQEIGK---------------------------------- 158
            .|:.:|..|...|:..|:.:: ..:|||..|
Human   131 RWEEVRGALMSAFSPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLSKPSGIYVNLHYATLPF 195

  Fly   159 ----------DLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNY 213
                      ||.||..:|..::..:|  :|:.....::||.:|::|||...:|.:.|...|..:
Human   196 CMVPLISQACDLLLAHLKRYAESGDAF--DIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKH 258

  Fly   214 GRKMFTFTVARAKDFFVAFFLPKLVSLMRI------QFFTADFSHFMRSTIG----HVMEERERS 268
            .::.|.|.:.|.....:..|...:|.|.||      ......|:..:|:.|.    ...|||
Human   259 CKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEER--- 320

  Fly   269 GLLRNDLIDVLVSLRKEAA--------------------AEPSKPHYAK------NQDFLVAQAG 307
               |.|.:.:::..|..|:                    ..||:.|...      ..|.:|.||.
Human   321 ---RRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAF 382

  Fly   308 VFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINE-----------ALVEGGGSLSYEKIQSL 361
            :|..||:|..::|:|||.|.:|.:|:.|::|..|::.           :|.||           |
Human   383 IFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEG-----------L 436

  Fly   362 EYLAMVVDEVLRMYPVLPFLDREYE---SVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKY 423
            .||.||:.|.|||||......||..   .|.||           .:..|..:.:.:.||||||::
Human   437 PYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ-----------RIPAGAVLEMAVGALHHDPEH 490

  Fly   424 WTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATM 488
            |.:|..|:||||:...|:......|.|||:||.:|:|.|:|||:.||.|:.:|.....:.|..|.
Human   491 WPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQ 555

  Fly   489 KDMKFDPKGFVLQADGGIHLEIVN 512
            ..::.:.|. .|....|::::||:
Human   556 VPLQLESKS-ALGPKNGVYIKIVS 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_001286335.1	p450	56..508	CDD:278495	137/550 (25%)
TBXAS1	NP_001159725.2	p450	47..576	CDD:306555	143/574 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8447
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.820