Protein Alignment Cyp6g1 and CYP27C1

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001354431.1
• Gene: CYP27C1 / 339761
• HGNCID: 33480
• Length: 537
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 95/402 - (23%)
• Similarity: 169/402 - (42%)
• Gaps: 82/402 - (20%)

  Fly   143 SGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLENPN 207
            ||:|.|   ::.::.|.:.|.   |.:...|..:|.:.::..::|.:.:|||.:..|...|||..
Human   184 SGEVNQ---VIADLIKRIYLL---RSQAEDGETVTNVNDLFFKYSMEGVATILYESRLGCLENSI 242

  Fly   208 AE------------FRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMRIQFFTADFSHFMRSTIG- 259
            .:            |..:...|:...:.|    ::..|:||            .:..|.||..|
Human   243 PQLTVEYIEALELMFSMFKTSMYAGAIPR----WLRPFIPK------------PWREFCRSWDGL 291

  Fly   260 ------HV----------MEERER--SGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQA 306
                  ||          |:...|  .|||....:...::|::         .||...:.|:
Human   292 FKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQE---------IYANVTEMLL--- 344

  Fly   307 GVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEV 371
                 ||.:|:|.|:|:.:|.:|:|||:|:.:..||.:.|.|.....:.: :..:..:..::.|.
Human   345 -----AGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAAD-VPKVPLVRALLKET 403

  Fly   372 LRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERF- 435
            ||::||||...|     ..|.||.:.   .|.:..||.:.:..||..:..:.:....:|.|||:
Human   404 LRLFPVLPGNGR-----VTQEDLVIG---GYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWL 460

  Fly   436 SPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVL 500
            ...:...:......|||.|..:|||.||..|:..|.::.||::..::....| ..:.....| :|
Human   461 RKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQT-NAVHAKTHG-LL 523

  Fly   501 QADGGIHLEIVN 512
            ...|.||:..||
Human   524 TPGGPIHVRFVN 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	91/395 (23%)
CYP27C1	NP_001354431.1	CYP27C1	98..530	CDD:410740	91/395 (23%)