Protein Alignment Cyp6g1 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 124/547 - (22%)
• Similarity: 216/547 - (39%)
• Gaps: 104/547 - (19%)

  Fly     2 VLTEVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTP---IIGNTKVVFKMENSFGMHLSEIY 63
            |||.:|.:...|...|       |..|..:.....|..|   ..|:.   ...:..|...|:.:.
  Rat    24 VLTVLLLLFKTAQFYL-------HRRWLLRATQQFPSPPSHWFFGHK---IPKDQEFQDILTRVK 78

  Fly    64 NDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDA 128
            |.|....:.:.|    :...:.:.|.:.:|.||.:...:.|:.|....|.   :|| .|..:...
  Rat    79 NFPSACPQWLWG----SNVRIQVYDPDYMKLILGRSDPKSHHSYRFLAPW---IGY-GLLLLNGQ 135

  Fly   129 HWKGIRTKLTPVFTSGKVKQMYTLM------------QEIGKDLELALQRRGEKNSGSFITEIKE 181
            .|...|..|||.|....:|....:|            |.:|:|..|               ||.:
  Rat   136 TWFQHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQDSTL---------------EIFQ 185

  Fly   182 ICAQFSTDSIATIAFGIRAN-SLENPNAEFRNYGRKMFTFTVARAKDFF----VAFFLP----KL 237
            .....:.|:|...||....: .|:.....:......:...:..|.::.|    :.:.|.    |.
  Rat   186 HITLMTLDTIMKCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKA 250

  Fly   238 VSLMRIQFFTADFSHFMRSTIGHVMEERERSGL---LRNDLIDVLVSLRKEAAAEPSKPHYAKNQ 299
            .|..::.....|  ..::|....:.:|.|...:   .|.|.:|:|:..|.|..:..|      ::
  Rat   251 RSAWQLAHEHTD--QVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLS------DK 307

  Fly   300 DFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYL 364
            | |.|:...|...|.:|::|.:|:..|.:|.:||.|:..|.|| ::|:..|.|::::.:..:.|.
  Rat   308 D-LRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEI-QSLLGDGASITWDDLDKMPYT 370

  Fly   365 AMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQ 429
            .|.:.|.||:||.:..:.|...:....||       ..:|..|..|.:..|.|||:|..|.||..
  Rat   371 TMCIKEALRIYPPVTAVSRMLSTPVTFPD-------GRSLPKGITVMLSFYGLHHNPTVWPNPEV 428

  Fly   430 FDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKF- 493
            |||.||:|.:.::  :.::.||..|..||||.:..:.:.|:.:...|              ::|
  Rat   429 FDPYRFAPESSRH--SHSFLPFSGGARNCIGKQFAMNELKVAVALTL--------------LRFE 477

  Fly   494 ---DP-------KGFVLQADGGIHLEI 510
               ||       ...||::..||:|.:
  Rat   478 LLPDPTRIPIPIPRLVLKSKNGIYLRL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	107/472 (23%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	112/488 (23%)