Protein Alignment Cyp6g1 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 166/527 - (31%)
• Similarity: 279/527 - (52%)
• Gaps: 60/527 - (11%)

  Fly     5 EVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLK 69
            |...::..:|:..|.:...:|..:::.|||...|.|:.|   .:|    ::|..:.:..:|...|
  Rat    10 ETWVLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFG---TIF----NYGDGMWKFDDDCYKK 67

  Fly    70 DEAVVGIYSMNKPGLIIRDIELIKSILIKD-FNRFHNRYARCDPHGDPLGY--NNLFFVRDAHWK 131
            ...:.|.|...:|.|.|.|.|:||.:|:|: ::.|.||  ||   ..|:|:  ..:....|..||
  Rat    68 YGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNR--RC---FGPMGFMKKAITMSEDEEWK 127

  Fly   132 GIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAF 196
            .:||.|:|.|||||:|:|:.||::.|..|...|:|  |:..|..| .:|:|...:|.|.|...:|
  Rat   128 RLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRR--EEAKGEPI-NMKDIFGAYSMDVITGTSF 189

  Fly   197 GIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMRIQFFT-----ADFSHFMRS 256
            |:..:||.||...|....:|:..|.:          |.|.|:|::...|.|     .:||.|.|.
  Rat   190 GVNVDSLNNPQDPFVQKAKKILKFQI----------FDPFLLSVVLFPFLTPIYEMLNFSIFPRQ 244

  Fly   257 TIG-----------HVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFF 310
            ::.           :.::..::|   |.|.:.::::.:.....|..|   |.:...:.|||.:|.
  Rat   245 SMNFFKKFVKTMKKNRLDSNQKS---RVDFLQLMMNTQNSKGQESQK---ALSDLEMAAQAIIFI 303

  Fly   311 TAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMY 375
            ..|::.:|:::||.:||:|..|.:||:|::||:.|| .....::|:.:..:|||.|||:|.||:|
  Rat   304 FGGYDATSTSISFIMYELATRPNVQKKLQNEIDRAL-PNKAPVTYDALMEMEYLDMVVNESLRLY 367

  Fly   376 PVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANR 440
            |:...|||     ..:.|:.:...:   :..||.|.||||.||.:|:||..|.:|:|||||..|:
  Rat   368 PIATRLDR-----VSKKDVEINGVF---IPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENK 424

  Fly   441 KNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGG 505
            .:|....|.|||:||.||||.|..|:..||.::.:|:|.:::.||.|...:|...:. :.|.:|.
  Rat   425 GSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKTQIPLKISRQP-IFQPEGP 488

  Fly   506 IHLEIVN 512
            |.|::|:
  Rat   489 IILKLVS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	150/456 (33%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	151/458 (33%)