Protein Alignment Cyp6g1 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 135/554 - (24%)
• Similarity: 214/554 - (38%)
• Gaps: 112/554 - (20%)

  Fly     1 MVLTEVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTP--IIGNTKVVFKMENSFGMHLSEIY 63
            :.|...|.:|:...|.||...||    ..|...|:..||.  ::|:.|  |..|:
  Rat    16 LALVFCLALVLMQAVKLYLRRQR----LLRDLRPFPGPTAHWLLGHQK--FLQED---------- 64

  Fly    64 NDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRY---------ARCDPHGD---- 115
                          :|.|...|:::........:..|..|...|         :|.||...
  Rat    65 --------------NMEKLDEIVKEYPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKTQYLHQ 115

  Fly   116 ---PLGYNNLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEK--NSGSF 175
               |.....|..:....|...|..|||.|....:|....:|   ...:.:.|. :.||  .:...
  Rat   116 LMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMM---AHSVNMMLD-KWEKTWTTQET 176

  Fly   176 ITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSL 240
            ..|:.|.....:.|.|...|||...|.  ..|..:.:|.:              ..|.|.:::|.
  Rat   177 TIEVFEHINLMTLDIIMKCAFGQETNC--QINGTYESYVK--------------ATFELGEIISS 225

  Fly   241 MRIQFFTADFSHFMRSTIGHVMEERERSGLLRNDLIDVLVSLRKEAAAEP-SKPHYAKNQDF--- 301
            ....|:......|..|..||..:|   .|.:.:...:.::..||:...:. ::.....:|:|
  Rat   226 RLYNFWHHHDIIFKLSPKGHCFQE---LGKVIHQCTEKIIQDRKKTLKDQVNQDDTQTSQNFLDI 287

  Fly   302 -LVAQAG---------------VFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGG 350
             |.||||               .|..||.:.|::::|:.||.:|.:||.|.|.|.||...|.: |
  Rat   288 VLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD-G 351

  Fly   351 GSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIY 415
            .|:::|::..:.|..|.:.|.||:.|.:|.:.||.......||       .::|..|..|.:.|:
  Rat   352 SSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPD-------GHSLPAGMTVVLSIW 409

  Fly   416 ALHHDPKYWTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHS 480
            .|||:|..|.:|..|||.||:..|.:.....|:.||.|||.||||.:..:|:.|:.:...|....
  Rat   410 GLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFR 474

  Fly   481 VRNCEATMKDMKFDPKGF----VLQADGGIHLEI 510
            |. .:.|.      |..|    ||:...||:|.:
  Rat   475 VA-ADLTR------PPAFSSHTVLRPKHGIYLHL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	117/479 (24%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	118/471 (25%)