Protein Alignment Cyp6g1 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 503
• Identity: 137/503 - (27%)
• Similarity: 236/503 - (46%)
• Gaps: 68/503 - (13%)

  Fly     1 MVLTEVLFVVVAALVALYTWFQRNHSYWQRK---GIPYIPPTPIIGNTKVVFKMENSFGMHLSEI 62
            :::...:|..:...::...|  |.|:.::.:   |||..|...:.||..::....:..|
 Worm     3 ILIISTIFFTIITFISYSIW--RRHAIFKLRSSIGIPGPPVHWLWGNLNIIKDRVSRLG------ 59

  Fly    63 YND-----PRL--KDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYN 120
            |||     |.|  |...:.|:|...:..:.:.:.|.||.|.|::|:.|.:|..     .|..|.|
 Worm    60 YNDTTQWHPTLHTKYGPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMT-----PDIFGMN 119

  Fly   121 --NLFFVRDAH---WKGIRTKLTPVFTSGKVKQMY-TLMQEIGKDLELALQRRGEKNSGSFITEI 179
              |...:::.:   ||..|:.:.|:|::||:|.|: ||:.:|    ::.|:...||:|.....:|
 Worm   120 QLNQSLLQNTYATGWKHTRSAIAPIFSTGKMKAMHETLVSKI----DIFLEVLKEKSSSGQKWDI 180

  Fly   180 KEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFF--VAFFLPKLVSLMR 242
            .|.....|.|.|...||.|.:|...:....|....|| |...|...|.:.  |:..||:|..|.|
 Worm   181 FENFQSLSLDIIGKCAFAIDSNCQRDRTDLFYVQARK-FVGAVDLKKSWILPVSLILPELSWLWR 244

  Fly   243 IQFFTADFSHFMRSTIGHVME--ERERSGLLRNDLIDVL-VSLRKEAAAEPSKPHYAKNQDFLVA 304
            ..:..:|.|......:..:::  :|.|:|...||..|:| :.:|:|...:.::....:|
 Worm   245 FLYKFSDLSAAELPLVKGLVDLYDRRRAGEGGNDSTDLLNLLIRRETIGKMTQREVIEN------ 303

  Fly   305 QAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVD 369
             ...|..||:||:|:.|.|:.|.:|::|.:|::|.:||.:.....|  |:|:.|.:::||..|..
 Worm   304 -CFAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKENAG--LNYDSIHNMKYLDCVYK 365

  Fly   370 EVLRMY-PVLPFLDR---EYESVEGQ--PDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPS 428
            |.||.| |...|.:|   ...::.||  |:       |.||:      :..|.:|.:|..|.:|.
 Worm   366 ESLRFYPPTTHFTNRVCLNDMTIRGQIYPE-------DSTLK------VQPYTIHRNPANWESPD 417

  Fly   429 QFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLL 476
            :|.||||.....|: .::.:.|||.||..|:|.|...::.|..:..||
 Worm   418 EFQPERFENWEEKS-SSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	121/425 (28%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	121/425 (28%)