Protein Alignment Cyp6g1 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 515
• Identity: 165/515 - (32%)
• Similarity: 272/515 - (52%)
• Gaps: 36/515 - (6%)

  Fly     5 EVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLK 69
            |...::..:||.||.:...:|..:::.|||...|.|.:|   .:...:..|.    |.......|
Mouse    10 ETWMLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLG---TILAYQKGFW----ECDIQCHKK 67

  Fly    70 DEAVVGIYSMNKPGLIIRDIELIKSILIKD-FNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGI 133
            ...:.|:|...:|.|.|.|.::||::|:|: ::.|.|| .|..|.|  :....:....:..||.|
Mouse    68 YGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNR-RRFGPVG--ILKKAISISENEEWKRI 129

  Fly   134 RTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGI 198
            |..|:|.||||::|:|:.::.:. .|:.:...|:|......  |.:|:|...:|.|.|...:||:
Mouse   130 RALLSPTFTSGRLKEMFPIINQF-TDVLVRNMRQGLGEGKP--TSMKDIFGAYSMDVITATSFGV 191

  Fly   199 RANSLENPNAEFRNYGRKMFTFTVARAKDFFVAF--FLPKLVSLMRIQFFTADFSHFMRSTIGHV 261
            ..:||.||...|....:|:..|.:.......|..  ||..:...:.:..|..|...|..:::..:
Mouse   192 NIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPRDVISFFTTSVERM 256

  Fly   262 ----MEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSSSTMS 322
                |:|:|:.   |.|.:.::::.:.....|   .|.|.:...:|||:.:|..||:||:||.:|
Mouse   257 KENRMKEKEKQ---RVDFLQLMINSQNYKTKE---SHKALSDVEIVAQSVIFIFAGYETTSSALS 315

  Fly   323 FALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYES 387
            ||||.:|.||::||:|:|||:.|| ......:|:.:..:|||.|||:|.||:||:...|:|..::
Mouse   316 FALYLLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKT 379

  Fly   388 VEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMAYQPFG 452
                 |:.:...:   :..||.|.||.:|||.|||||..|.:|.|||||..|:.:|....|.|||
Mouse   380 -----DVEINGLF---IPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYLPFG 436

  Fly   453 SGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIVN 512
            |||.||||.|..|:..|:.||.:|:|.:|:.|:.|...:|...:| :||.:..:.|::|:
Mouse   437 SGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQG-LLQPENPLLLKVVS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	149/444 (34%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	149/446 (33%)