Protein Alignment Cyp6g1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 519
• Identity: 169/519 - (32%)
• Similarity: 276/519 - (53%)
• Gaps: 45/519 - (8%)

  Fly     5 EVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLK 69
            |...::..:||.||.:..|.|..::::|||...|.|.:|.....:|....|.|...:.|.
Mouse    10 ETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYKKYG----- 69

  Fly    70 DEAVVGIYSMNKPGLIIRDIELIKSILIKD-FNRFHNRYARCDPHGDPLGYNN--LFFVRDAHWK 131
              ...|::....|.|.:.|.|.||::|:|: |:.|.||     ....|:|..:  :...:|..||
Mouse    70 --KTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNR-----RDFGPVGIMSKAISISKDDEWK 127

  Fly   132 GIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAF 196
            ..|..|:|.|||||:|:|:.::::.|..|...|:::.:|  |..:| :|::...:|.|.|.:.:|
Mouse   128 RYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKK--GKPVT-MKDVLGAYSMDVITSTSF 189

  Fly   197 GIRANSLENPNAEFRNYGRKMFTFTVARAKDFF-------VAF-FLPKLVSLMRIQFFTADFSHF 253
            |:..:||.||...|....:|:..|      |||       |.| ||..:..::.|..|..|...|
Mouse   190 GVNVDSLNNPEDPFVEKAKKLLRF------DFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEF 248

  Fly   254 MRSTIGHVMEER-ERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETS 317
            .:..:..:.|.| :.....|.|.:.::::....:..:.|  |.|.:...:.||:.:|..||:||:
Mouse   249 FKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVS--HKALSDMEITAQSIIFIFAGYETT 311

  Fly   318 SSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLD 382
            |||:||.|:.:|.||::||:|:|||:||| ......:|:.:..:|||.||::|.||:||:...|:
Mouse   312 SSTLSFTLHSLATHPDIQKKLQDEIDEAL-PNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLE 375

  Fly   383 REYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMA 447
            |..:.     |:.|...|   :..|:.|.||.|||||||::|:.|.:|.|||||..|:.:|....
Mouse   376 RVCKK-----DVELNGVY---IPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYV 432

  Fly   448 YQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIV 511
            |.|||:||.||:|.|..|:..||.|..:::|.|.:.|:.|...:|...:| :||.:..|.|::|
Mouse   433 YLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQG-LLQPEKPIVLKVV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	149/449 (33%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	151/458 (33%)