Protein Alignment Cyp6g1 and cyp3a4

DIOPT Version :10

• Sequence 1: NP_610743.2
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_002943949.2
• Gene: cyp3a4 / 100494419
• XenbaseID: XB-GENE-984218
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 167/525 - (31%)
• Similarity: 261/525 - (49%)
• Gaps: 53/525 - (10%)

  Fly     4 TEVLFVVVAALVALY-TWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPR 67
            |.:|..|:..|:.|| .|   .:..:::.|||...|.|.||......|....|.:...:.|.
 Frog    11 TWILLAVLLVLILLYGIW---PYGLFKKMGIPGPTPLPFIGTFLEFRKGMIQFDIECFKKYG--- 69

  Fly    68 LKDEAVVGIYSMNKPGLIIRDIELIKSILIKD-FNRFHNRYARCDPHGDPLGYNN-----LFFVR 126
                .:.|:|...:|.|.|.|..:||:||:|: :..|.||        ...|.|.     :....
 Frog    70 ----RMWGMYDGRQPVLAIMDPAIIKTILVKECYTNFTNR--------RNFGLNGPLESAITVAE 122

  Fly   127 DAHWKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSI 191
            |..||.||:.|:|.|||||:|:|:.:|::....|...:|...:|:..   ...|::...:|.|.|
 Frog   123 DEQWKRIRSVLSPTFTSGKLKEMFQIMKDYSDILVKNVQVSVDKDEP---CATKDVIGAYSMDVI 184

  Fly   192 ATIAFGIRANSLENPNAEF----RNYGRKMFTFTVARAKDFFVAF-FLPKLVSLMRIQFFTADFS 251
            .:.:|.:..:||:||:..|    :|..:..|...|.   .|.|.| ||..:..::.|.||..||:
 Frog   185 TSTSFSVNIDSLQNPSNPFVIHIKNLLKTGFLSPVI---IFAVIFPFLRPIFEVLNISFFPKDFT 246

  Fly   252 HFMRSTIGHVMEERER---SGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAG 313
            .|..:.:....|:|::   ||  |.||:.::|........:.|..|.|.....::||:.:|..||
 Frog   247 QFFMNAVTSFREKRKKGDHSG--RVDLLQLMVDSGTTEGNDSSNQHKALTDAEIMAQSLIFIFAG 309

  Fly   314 FETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVL 378
            :||:|:.:|:..|.:|.||::|::|.:||:..|.: ..|.:|:.:..:|||.||:.|.||::|..
 Frog   310 YETTSTALSYLFYNLATHPDVQQKLHEEIDSFLPD-KASPTYDILMQMEYLDMVIQETLRLFPPA 373

  Fly   379 PFLDR-EYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKN 442
            ..|:| ..::||         ....::..||...||.|.|..||:||..|.:|.|||||..||..
 Frog   374 GRLERVSKQNVE---------INGVSIPKGTVAMIPAYVLQRDPEYWPEPEEFRPERFSKENRAT 429

  Fly   443 IVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIH 507
            .....:.|||.||.||||.|..||..|:.:.:||:|.|||.|..|:..|:|...| |||....|.
 Frog   430 QTPFTFLPFGDGPRNCIGLRFALLSMKVAIATLLQNFSVRPCAETLIPMEFSTIG-VLQPKKPIV 493

  Fly   508 LEIVN 512
            |:.::
 Frog   494 LKFLS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6g1	NP_610743.2	CYP6-like	69..507	CDD:410679	148/452 (33%)
cyp3a4	XP_002943949.2	CYP3A	67..495	CDD:410743	150/461 (33%)