Protein Alignment wash and Washc1

DIOPT Version :9

• Sequence 1: NP_001286334.1
• Gene: wash / 36311
• FlyBaseID: FBgn0033692
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001120862.1
• Gene: Washc1 / 367328
• RGDID: 1310196
• Length: 475
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 172/521 - (33%)
• Similarity: 242/521 - (46%)
• Gaps: 95/521 - (18%)

  Fly    11 YQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDAL 75
            |.|.:|..||..|:.|.|.|.:|..|......||.||..|:..:..:::.|..||..|||||:.:
  Rat    15 YAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISQRVELSRRQLQAIGERVSLAQAKIEKI 79

  Fly    76 VGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADI- 139
            .|||:||::|:.|::||.:.|....:.|.. |.:|.::::.....|   |.|...|::.....:
  Rat    80 KGSKKAIKVFSSAKYPAPEHLQEYNSVFTG-ALDPGLQRRPRYRIQ---SKHRPLDERALQEKLK 140

  Fly   140 FFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKR--SLP 202
            :|.|....:.|....||.       |||.||: .:.|:.||:.|||.|       |.:|:  .|.
  Rat   141 YFPVCVSTKSEPEDEAEE-------GLGGLPS-NISSISSLLLFNTTE-------NLYKKYVFLD 190

  Fly   203 PQNARRVASQSTQL-TGEKQLAPAPHSLAHGTTKLATPAGD-LRYNPAALAAPAIDVPLDLPDLP 265
            |. |..|....|.| |.|::|..||.|::. ..:|..||.: ..|.|.....|.||||..|||||
  Rat   191 PL-AGAVTKTHTMLGTEEEKLFDAPLSISK-REQLEQPAPENYFYVPGLGQVPEIDVPSYLPDLP 253

  Fly   266 GIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVR-RKSVGQCPS 329
            |:|:||.|. .:....||||.. |.:||||              |..|.:..|.: .:..|
  Rat   254 GVADDLMYS-ADLGPGIAPSAP-GAIPELP--------------AFHTEVAEPFQPEREDG---- 298

  Fly   330 PVTAAPPPPPPPPPPPPPPPPAQTSAIPSPPPFPTKGAVKPLSPSLAT----------------- 377
               |...|||||||||||||||.|:.:.:|.|        |:||.:.|
  Rat   299 ---ALLAPPPPPPPPPPPPPPAPTAVVSAPQP--------PMSPDVVTVTGKVAREEDSGSGEAH 352

  Fly   378 PLNMPQPPPATEDP---RSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVT--GDLM 437
            ..::...|....||   |:.|:.:||.|||:...:|||.....|:.......:...|.:  ||||
  Rat   353 SASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLM 417

  Fly   438 ADLHNKLMLRRKGISGSQNPVEATAGNP-----LMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDG 497
            :||.|||::||||||| :.|...|:..|     .|......:|||.||.         .::|||.
  Rat   418 SDLFNKLVMRRKGISG-KGPGTGTSEGPGGAFSRMSDSIPPLPPPQQPA---------GDEDEDD 472

  Fly   498 W 498
            |
  Rat   473 W 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wash	NP_001286334.1	WASH_WAHD	11..301	CDD:288773	101/294 (34%)
Washc1	NP_001120862.1	WHD1	1..167		51/163 (31%)
		Required for WASH complex assembly. /evidence=ECO:0000250|UniProtKB:C4AMC7	1..54		15/38 (39%)
		WASH_WAHD	14..296	CDD:288773	104/317 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..475		68/203 (33%)
		VCA. /evidence=ECO:0000250|UniProtKB:C4AMC7	357..475		44/127 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346535
Domainoid	1	1.000	109	1.000	Domainoid score	I6258
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45706
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3791
OMA	1	1.010	-	-		QHG54361
OrthoDB	1	1.010	-	-		D386666at33208
OrthoFinder	1	1.000	-	-		FOG0004493
OrthoInspector	1	1.000	-	-		oto97484
orthoMCL	1	0.900	-	-		OOG6_105225
Panther	1	1.100	-	-	LDO	PTHR23331
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3782
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910