DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EndoG and Endog

DIOPT Version :9

Sequence 1:	NP_610737.1	Gene:	EndoG / 36309	FlyBaseID:	FBgn0033690	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001030110.1	Gene:	Endog / 362100	RGDID:	1310763	Length:	294	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	157/316 - (49%)
Similarity:	194/316 - (61%)	Gaps:	29/316 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAPRVGGVLALGATALGAFYLGTHVERERQHNGSTSG-LPRLPGLPTFGTVSAASLIPAQENNV 64
            |.|.|.|..|||||.      ||...|..|:..|...| |.|:|.||    |.||.| ||
  Rat     1 MRALRAGLTLALGAG------LGAAAEHWRRREGKGPGLLGRVPVLP----VVAADL-PA----- 49

  Fly    65 SLTATPS-RIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCD 128
             |...|: ..|::.|||.||:..:||...||||||.|.|...||.|.|..|.: :.|. ||..||
  Rat    50 -LPGGPAGSTGELAKYGLPGVAQLRSRESYVLSYDPRTRGALWVLEQLRPERL-RGDG-DRRACD 111

  Fly   129 FKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNT 193
            |.:|:|:|.:.|:.|.|||.||:||||:|||.|||..|:..|:||||||:||||.. .|:.|||.
  Rat   112 FHEDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPH-LNQHAWNN 175

  Fly   194 LEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLH 258
            ||.:.|.||:||.|||||||||:||..|.||||||||:|||.|.|||||||:||::.|:|..::.
  Rat   176 LEKYSRSLTRTYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAASGQIE 240

  Fly   259 MESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQI-----NRKQLTTINGKK 309
            :.||||||..:....|:..|.||.||:||::||||...|     |.|.:|.  |.|
  Rat   241 LRSYVMPNAPVDETLPLERFLVPIESIERASGLLFVPNILARAGNLKAITA--GSK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoG	NP_610737.1	NUC1	39..305	CDD:224777	140/271 (52%)
EndoG	NP_610737.1	NUC	77..309	CDD:238043	127/236 (54%)
Endog	NP_001030110.1	NUC	75..281	CDD:214683	116/208 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340552
Domainoid	1	1.000	251	1.000	Domainoid score	I2038
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55823
Inparanoid	1	1.050	264	1.000	Inparanoid score	I3005
OMA	1	1.010	-	-		QHG52002
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	1	1.000	-	-		FOG0003231
OrthoInspector	1	1.000	-	-		otm44618
orthoMCL	1	0.900	-	-		OOG6_102078
Panther	1	1.100	-	-	LDO	PTHR13966
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3743
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770