DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EndoG and ENDOD1

DIOPT Version :9

Sequence 1:	NP_610737.1	Gene:	EndoG / 36309	FlyBaseID:	FBgn0033690	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_055851.1	Gene:	ENDOD1 / 23052	HGNCID:	29129	Length:	500	Species:	Homo sapiens

Alignment Length:	171	Identity:	41/171 - (23%)
Similarity:	65/171 - (38%)	Gaps:	49/171 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 YDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDE----------------SIHPFFRSQ--N 143
            |..|:|:|  |:....|...|...|..|...:.:.|:                |::.....|  |
Human    69 YSTRDRIP--VYSAFRAPRPAPGGAEQRWLVEPQIDDPNSNLEEAINEAEAITSVNSLGSKQALN 131

  Fly   144 TDYRRSGYDRGHM---AAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAW--NTLEAHVRRLTK 203
            |||..|.|.||.:   :.:.:.::      .||.|:|.||.. |.| ::.|  |......|.||.
Human   132 TDYLDSDYQRGQLYPFSLSSDVQV------ATFTLTNSAPMT-QSF-QERWYVNLHSLMDRALTP 188

  Fly   204 ---TYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVP 241
               :..::|:.||.:...::..|             .||||
Human   189 QCGSGEDLYILTGTVPSDYRVKD-------------KVAVP 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoG	NP_610737.1	NUC1	39..305	CDD:224777	41/171 (24%)
EndoG	NP_610737.1	NUC	77..309	CDD:238043	41/171 (24%)
ENDOD1	NP_055851.1	NUC	65..281	CDD:294067	41/171 (24%)
ENDOD1	NP_055851.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910