Protein Alignment EndoG and ENDOG

DIOPT Version :9

• Sequence 1: NP_610737.1
• Gene: EndoG / 36309
• FlyBaseID: FBgn0033690
• Length: 310
• Species: Drosophila melanogaster
• Sequence 2: XP_011516649.1
• Gene: ENDOG / 2021
• HGNCID: 3346
• Length: 338
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 106/219 - (48%)
• Similarity: 135/219 - (61%)
• Gaps: 17/219 - (7%)

  Fly     1 MSAPRVGGVLALGATALGAFYLGTHVERERQHNGSTSG-LPRLPGLPTFGTVSAASLIPAQENNV 64
            |.|.|.|..||.|| .|||...|.  .|.|:...:..| |.|||.||    |:||:.:|
Human    90 MRALRAGLTLASGA-GLGAVVEGW--RRRREDARAAPGLLGRLPVLP----VAAAAELP------ 141

  Fly    65 SLTATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDF 129
            .:...|...|::.|||.|||..::|...|||.||.|.|...||.|.|..|.: :.|. ||.:|||
Human   142 PVPGGPRGPGELAKYGLPGLAQLKSRESYVLCYDPRTRGALWVVEQLRPERL-RGDG-DRRECDF 204

  Fly   130 KQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTL 194
            ::|:|:|.:.|:.|.|||.||:||||:|||.|||..||..|:||||||:||||.. .|::|||.|
Human   205 REDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPH-LNQNAWNNL 268

  Fly   195 EAHVRRLTKTYSNVYVCTGPLYLP 218
            |.:.|.||::|.|||||||||:||
Human   269 EKYSRSLTRSYQNVYVCTGPLFLP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoG	NP_610737.1	NUC1	39..305	CDD:224777	91/180 (51%)
		NUC	77..309	CDD:238043	79/142 (56%)
ENDOG	XP_011516649.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146898
Domainoid	1	1.000	249	1.000	Domainoid score	I2130
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55823
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3092
Isobase	1	0.950	-	0	Normalized mean entropy	S973
OMA	1	1.010	-	-		QHG52002
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	1	1.000	-	-		FOG0003231
OrthoInspector	1	1.000	-	-		otm40477
orthoMCL	1	0.900	-	-		OOG6_102078
Panther	1	1.100	-	-	LDO	PTHR13966
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R945
SonicParanoid	1	1.000	-	-		X3743
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750