DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EndoG and exog

DIOPT Version :9

Sequence 1:	NP_610737.1	Gene:	EndoG / 36309	FlyBaseID:	FBgn0033690	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	XP_031760009.1	Gene:	exog / 100486077	XenbaseID:	XB-GENE-981839	Length:	353	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	111/296 - (37%)
Similarity:	160/296 - (54%)	Gaps:	38/296 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GVLALGATALGAFYLGTHVERERQHNGSTSGLPRLPGLPTFGTVSAASLIPAQENNVSLTATPSR 72
            |...|||.|..|..|......||:.       |:|           |.:.|.|::
Frog    11 GGFVLGAAASSASCLAALQLYERRE-------PQL-----------APVAPVQKD---------- 47

  Fly    73 IGQIMKYGFP--GLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESI 135
              .:.:||||  |.: .|.:.::.||||...|.|.||.|||:...:.  .:.||..|.||.|.:|
Frog    48 --PLEEYGFPLTGYE-ARHYINHALSYDPAKRTPKWVIEHLSGTKIV--GSADRKHCKFKPDPNI 107

  Fly   136 HPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRR 200
            ...|.:.|.||.|||:.|||||.||:::...:...|||||||:.||..:. |...||.:|.:.|.
Frog   108 PKMFSATNEDYLRSGWTRGHMAPAGDNKFSTEAMAETFYLSNIVPQNYEN-NAGFWNRMEMYCRD 171

  Fly   201 LTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIV--GESADHKLHMESYV 263
            |||.:.:|:|.:|||.||...:|||..|.||||||:.|:||:|.||||:  |:.::..|.:.::|
Frog   172 LTKRFEDVWVVSGPLELPTLHEDGKKRVMYEVIGADDVSVPSHLYKVILVRGKGSEQPLAVGAFV 236

  Fly   264 MPNQVISNDTPISVFQVPPESVERSAGLLFFDQINR 299
            :||..|..|..:..:||..|.:|:.:||:||.|::|
Frog   237 VPNSPIGFDRQLPEYQVQLEDLEKMSGLVFFPQLDR 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoG	NP_610737.1	NUC1	39..305	CDD:224777	102/265 (38%)
EndoG	NP_610737.1	NUC	77..309	CDD:238043	97/227 (43%)
exog	XP_031760009.1	NUC	66..273	CDD:214683	91/210 (43%)
exog	XP_031760009.1	Exog_C	292..336	CDD:407864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010