DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EndoG and endog

DIOPT Version :9

Sequence 1:	NP_610737.1	Gene:	EndoG / 36309	FlyBaseID:	FBgn0033690	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001019385.1	Gene:	endog / 100002293	ZFINID:	ZDB-GENE-050522-402	Length:	306	Species:	Danio rerio

Alignment Length:	291	Identity:	139/291 - (47%)
Similarity:	183/291 - (62%)	Gaps:	14/291 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LALGATALGAFYLGTHVERERQHNGSTSGLPRLPGLPTFGTVSAASLIPAQENNVSLTATPSRIG 74
            :.:|||.       |.....|.:|...|.|.|:|.:|.....:|:.:.|.|...||:    :|..
Zfish    20 IGIGATL-------TAAGDRRNNNRKASLLDRVPVIPIPSVDAASEISPYQPGQVSV----NRST 73

  Fly    75 QIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFF 139
            ..||||||.|.:::|...||.|||.|||...||.|.|.||:|..:.  ||..|:||:|||:|.:.
Zfish    74 AAMKYGFPSLSNIKSRESYVTSYDPRNRTAAWVIEQLNAETVTGSS--DRKYCEFKEDESVHVYH 136

  Fly   140 RSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKT 204
            ||.|.||:.||:||||:|||.||:..||..||||||||::|| ....|::|||.||.:.|.|||.
Zfish   137 RSSNADYKGSGFDRGHLAAAANHKWSQKAMDETFYLSNVSPQ-NPNLNQNAWNNLEKYCRSLTKH 200

  Fly   205 YSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVI 269
            |.||:|||||||||.:|.|||.||||:|:|.|.|||||||:||::.|.....:.:.||||||..:
Zfish   201 YQNVFVCTGPLYLPRQEADGKMYVKYQVLGKNHVAVPTHFFKVVILEKPRGDVELRSYVMPNMPV 265

  Fly   270 SNDTPISVFQVPPESVERSAGLLFFDQINRK 300
            ....|:..|.||.||:||::||||...|.::
Zfish   266 DEKIPLERFLVPIESIERASGLLFVPNIMKR 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoG	NP_610737.1	NUC1	39..305	CDD:224777	132/262 (50%)
EndoG	NP_610737.1	NUC	77..309	CDD:238043	122/224 (54%)
endog	NP_001019385.1	NUC	89..293	CDD:214683	113/206 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580355
Domainoid	1	1.000	255	1.000	Domainoid score	I2015
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55823
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2999
OMA	1	1.010	-	-		QHG52002
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	1	1.000	-	-		FOG0003231
OrthoInspector	1	1.000	-	-		oto39279
orthoMCL	1	0.900	-	-		OOG6_102078
Panther	1	1.100	-	-	LDO	PTHR13966
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R945
SonicParanoid	1	1.000	-	-		X3743
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800