Protein Alignment CCT5 and CCT6A

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001753.1
• Gene: CCT6A / 908
• HGNCID: 1620
• Length: 531
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 163/522 - (31%)
• Similarity: 280/522 - (53%)
• Gaps: 40/522 - (7%)

  Fly    34 AIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAKLMVQLSQS 98
            |:..:|.|||.:...|:|:|||||..|::||..||:.:|.||..::..|::.|..|.|:.:::.:
Human    19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATA 83

  Fly    99 QDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLDAIAQPFPVDPKNK 163
            |||..|||||..|::.|.||:||:..|..|:||..|.:|||.|.:.|::.|:.:.....:|   :
Human    84 QDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMD---R 145

  Fly   164 EPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVL-NVADIEKKDVNFELIKIETKVGGRME------ 221
            |.||.:|.|:|.:|:    |.::|::..:||: ::..|:|:|...:|..||.     ||
Human   146 ETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIKKQDEPIDLFMIEI-----MEMKHKSE 201

  Fly   222 -DSMLVKGVIVDKTLSHSQMPKELRNVKLAILTC--PFEPPKPKTKHKLDVTSAEDYRALREYEQ 283
             |:.|::|:::|....|..|.|.:.:.  .||||  ..|..|.:........|||:...|.:.|:
Human   202 TDTSLIRGLVLDHGARHPDMKKRVEDA--YILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAER 264

  Fly   284 EKFTQMVKQV----------KDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIAT 338
            :.....||::          .|.| .:.|.|.|.|..:...|.::.:.|:|......:|.:.:|.
Human   265 KFIEDRVKKIIELKRKVCGDSDKG-FVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLAC 328

  Fly   339 GGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAKRSI 403
            ||..:..|::|:|:.||.||||.|...|  ::|...||:|.|.::||:.::|.|...:.:.|.::
Human   329 GGVALNSFDDLSPDCLGHAGLVYEYTLG--EEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAV 391

  Fly   404 HDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSG 468
            .|.:..|::.:.|..:|.|.||.|::.:.|:.|....:....|...:||:.||..||..||:|||
Human   392 RDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSG 456

  Fly   469 LHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLS-TQLVKMILKID 532
            ....|||.:::|.. :|....:||| :.:|:..:.:...|...:..|:|:|.| |.:...||.:|
Human   457 FDLQETLVKIQAEH-SESGQLVGVD-LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVD 519

  Fly   533 DV 534
            ::
Human   520 EI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	163/522 (31%)
CCT6A	NP_001753.1	chap_CCT_zeta	3..530	CDD:274088	163/522 (31%)