Protein Alignment CCT5 and CCT8

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_012526.1
• Gene: CCT8 / 853447
• SGDID: S000003545
• Length: 568
• Species: Saccharomyces cerevisiae
• Alignment Length: 524
• Identity: 147/524 - (28%)
• Similarity: 268/524 - (51%)
• Gaps: 24/524 - (4%)

  Fly    39 IMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAKLMVQLSQSQDDEI 103
            |.|.|::.....||:||.|.:||:|:..|.:.:|||.||:::.:::.|...|::|..::.|..::
Yeast    32 IAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLRELDIVHPAVKVLVMATEQQKIDM 96

  Fly   104 GDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLDAIAQPFPVDPKNKEPLIQ 168
            ||||..|::|||.||..:|.||..|:..:.|..|:.:|.:..:|:||.:......|..:|..|::
Yeast    97 GDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFTLKELDEMVVGEITDKNDKNELLK 161

  Fly   169 IAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKKD-----VNFELIKIETKVGGRMEDSMLVKG 228
            :....:.||.... ...::|:..:||.:|..:.::.     .|.:.|::...:||.:.:|.::||
Yeast   162 MIKPVISSKKYGS-EDILSELVSEAVSHVLPVAQQAGEIPYFNVDSIRVVKIMGGSLSNSTVIKG 225

  Fly   229 VIVDK-TLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREYEQEKFTQMVKQ 292
            ::.:: ...|.:...|.:..|:|:.|||.:....:||..:.:.:|::.....:.|:::...|:|:
Yeast   226 MVFNREPEGHVKSLSEDKKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKE 290

  Fly   293 VKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIATGGRIVPRFEELTPEKLGVA 357
            :.|.|....:...|..:.|.|.|.:..:..::.....|:..:....|...:||....|||:||:.
Yeast   291 IADMGVECIVAGAGVGELALHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRLGAPTPEELGLV 355

  Fly   358 GLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAKRSIHDAICVVRSLVKDS--RIV 420
            ..|:.|..|..:..:...|:.:.|:..||.|||.....:.:.:|:|.|.:..|:.|:|.|  :::
Yeast   356 ETVKTMEIGGDRVTVFKQEQGEISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLL 420

  Fly   421 YGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSGLHPIETLSEL-KARQVA 484
            .|.||.||.....:.|..::...|.|.|.:.|:||.|.:|..|||.:||...|.|..| .|..|.
Yeast   421 PGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAHNVT 485

  Fly   485 E----KKSSL--GVDCMLSGDS-----DMKSHNVVESLHSKKQQILLSTQLVKMILKIDD-VRSK 537
            |    |...|  |||  :.|:|     |::..|:.:.|.:||..|.::|:....:|.||. :.:|
Yeast   486 EPGAVKTDHLYKGVD--IDGESDEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAK 548

  Fly   538 NEGG 541
            ..||
Yeast   549 KAGG 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	144/517 (28%)
CCT8	NP_012526.1	chap_CCT_theta	9..559	CDD:274087	147/524 (28%)