Protein Alignment CCT5 and CCT4

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_010138.1
• Gene: CCT4 / 851412
• SGDID: S000002302
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 177/526 - (33%)
• Similarity: 315/526 - (59%)
• Gaps: 25/526 - (4%)

  Fly    21 RDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVD 85
            :::|:.:.:.     |.:|:|||.:|..::|||||||:||::.:..|::.::|||.||:|.|.:.
Yeast    12 KNKEKPQEVR-----KANIIAARSVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAIL 71

  Fly    86 HEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLD 150
            |.:|:::|::|.:||.|.|||||.||:|.||||..||.|:::||||..|||.|:.||:.::..|
Yeast    72 HPVARMLVEVSAAQDSEAGDGTTSVVILTGALLGAAERLLNKGIHPTIIADSFQSAAKRSVDIL- 135

  Fly   151 AIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKKDVNFELIKIETK 215
             :.....|...::|.|::.|.|:|.||||::....:|.:|||:||.::|...|:|:...|::..|
Yeast   136 -LEMCHKVSLSDREQLVRAASTSLSSKIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKK 199

  Fly   216 VGGRMEDSMLVKGVIVDKT-LSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALR 279
            |||.::|:.::.||::.:| :..:..|......|:.::.....||||.|::.:.|   .|||.:.
Yeast   200 VGGTIDDTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIV---NDYRQMD 261

  Fly   280 EYEQEK---FTQMVKQVKDAGATLAICQWGF-----DDEANHLLLQQELPAVRWVGGPEIELIAI 336
            :..:|:   ...:.|::|.|...:.:.|...     :|.|.|.|.:..:..|:.:...|||.::.
Yeast   262 KILKEERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSK 326

  Fly   337 ATGGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKA---VTIFLRGGNAMIIAE 398
            ..|.:.:...|..|.::||.|.||.|:  .:...|::.:...:|:.|   |::.:||.|.|||.|
Yeast   327 GLGCKPIADIELFTEDRLGSADLVEEI--DSDGSKIVRVTGIRNNNARPTVSVVIRGANNMIIDE 389

  Fly   399 AKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLAL 463
            .:||:|||:||:|.|||:..::.||||.||..|..::|||..:..::.:.::.|:.|||.||..|
Yeast   390 TERSLHDALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPTTL 454

  Fly   464 AENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMI 528
            |||:||:.|:.::||:::....:.:. |:....||.::....::::.:......|.|:::.||.|
Yeast   455 AENAGLNSIKVVTELRSKHENGELND-GISVRRSGTTNTYEEHILQPVLVSTSAITLASECVKSI 518

  Fly   529 LKIDDV 534
            |:|||:
Yeast   519 LRIDDI 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	177/526 (34%)
CCT4	NP_010138.1	chap_CCT_delta	11..528	CDD:274083	177/526 (34%)