DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT5 and AT1G24510

DIOPT Version :9

Sequence 1:	NP_523707.1	Gene:	CCT5 / 36308	FlyBaseID:	FBgn0010621	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_173859.1	Gene:	AT1G24510 / 839066	AraportID:	AT1G24510	Length:	535	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	339/531 - (63%)
Similarity:	438/531 - (82%)	Gaps:	0/531 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AFDEYGRPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTN 73
            ||||:||||||||:|:::.|:.|.||.|.:|.|.:.:|..|::||||||:||::..||||:|:||
plant     4 AFDEFGRPFIILREQDQKTRLRGIDAQKANIAAGKAVARILRSSLGPKGMDKMLQGPDGDITITN 68

  Fly    74 DGATIMKLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGF 138
            |||||::.|:||::||||||:||:|||.|||||||||||:|||||||||..:||||||||||:|:
plant    69 DGATILEQMDVDNQIAKLMVELSRSQDYEIGDGTTGVVVMAGALLEQAERQLDRGIHPIRIAEGY 133

  Fly   139 ELAAQCAIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKK 203
            |:|::.|::.|:.|||.|..|..|.|||:|..||||.|||||:|.|.:||:||.|||.|||:|::
plant   134 EMASRVAVEHLERIAQKFEFDVNNYEPLVQTCMTTLSSKIVNRCKRSLAEIAVKAVLAVADLERR 198

  Fly   204 DVNFELIKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLD 268
            |||.:|||:|.||||::||:.|:.|:::||.:||.||||::.:..:|||||||||||||||||:|
plant   199 DVNLDLIKVEGKVGGKLEDTELIYGILIDKDMSHPQMPKQIEDAHIAILTCPFEPPKPKTKHKVD 263

  Fly   269 VTSAEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIEL 333
            :.:.|.:..||:.||:.|.:||::.||.||||.||||||||||||||:.:.|||||||||.|:||
plant   264 IDTVEKFETLRKQEQQYFDEMVQKCKDVGATLVICQWGFDDEANHLLMHRNLPAVRWVGGVELEL 328

  Fly   334 IAIATGGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAE 398
            |||||||||||||:||||||||.||:|||.:|||:|::||.||.|.||||||:|:||||.|:|.|
plant   329 IAIATGGRIVPRFQELTPEKLGKAGVVREKSFGTTKERMLYIEHCANSKAVTVFIRGGNKMMIEE 393

  Fly   399 AKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLAL 463
            .|||||||:||.|:|:::..||||||||||:|||||...||:...:||||.|||:.||:|:|:||
plant   394 TKRSIHDALCVARNLIRNKSIVYGGGAAEIACSLAVDAAADKYPGVEQYAIRAFAEALDSVPMAL 458

  Fly   464 AENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMI 528
            ||||||.||||||.:|::|:.|.....|:||...|.:||:..||.|:|..|:|||||:||:||||
plant   459 AENSGLQPIETLSAVKSQQIKENIPFYGIDCNDVGTNDMREQNVFETLIGKQQQILLATQVVKMI 523

  Fly   529 LKIDDVRSKNE 539
            ||||||.|.:|
plant   524 LKIDDVISNSE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	335/524 (64%)
CCT5	NP_523707.1	Cpn60_TCP1	45..534	CDD:278544	315/488 (65%)
AT1G24510	NP_173859.1	TCP1_epsilon	6..531	CDD:239455	335/524 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	657	1.000	Domainoid score	I24
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6287
Inparanoid	1	1.050	700	1.000	Inparanoid score	I132
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D511484at2759
OrthoFinder	1	1.000	-	-		FOG0005168
OrthoInspector	1	1.000	-	-		oto3406
orthoMCL	1	0.900	-	-		OOG6_100235
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3688
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840