Protein Alignment CCT5 and CCT3

DIOPT Version :9

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_005989.3
• Gene: CCT3 / 7203
• HGNCID: 1616
• Length: 545
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 167/532 - (31%)
• Similarity: 304/532 - (57%)
• Gaps: 12/532 - (2%)

  Fly    15 RPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIM 79
            ||.::|  .:..||.:|......:|.||:.||..::|.||||.:.|:::.|.|.:.:||||..|:
Human     5 RPVLVL--SQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAIL 67

  Fly    80 KLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQC 144
            :.::|.|..||.|:::|::||:|:|||||.|::|||.:|..||..:::.:||..:...:..|...
Human    68 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDD 132

  Fly   145 AIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIE--KKDVNF 207
            .|..|..|:  .|||..:.:.::.|..:::.:|.:::.......:|:|||..|...|  :|:::.
Human   133 MISTLKKIS--IPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDI 195

  Fly   208 -ELIKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTS 271
             :..::|...||.:|||.:::||:::|.::|.:|.:.::|.::.:|....|..|.:::..:::|.
Human   196 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITR 260

  Fly   272 AEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAI 336
            .||:..:.:.|:|...|:.:.:......:.|.:.|..|.|.|.|::..:.|:|.|...:...||.
Human   261 EEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIAR 325

  Fly   337 ATGGRIVPRFEELTPEKLGV-AGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAK 400
            |.|.|||.|.|||..:.:|. |||:.....|  .:....|.:||:.||.||.|||.:..|::|.:
Human   326 ACGARIVSRPEELREDDVGTGAGLLEIKKIG--DEYFTFITDCKDPKACTILLRGASKEILSEVE 388

  Fly   401 RSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAE 465
            |::.||:.|.|:::.|.::|.||||:|::.:.|:.:::..::.:||:.:||.:.|||.||..|.:
Human   389 RNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQ 453

  Fly   466 NSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMILK 530
            |.|...|..|:.|:|:...|...:.||:.......|||...:.|.|..|.|....:.:...::|:
Human   454 NCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLR 518

  Fly   531 IDDVRS--KNEG 540
            |||:.|  |.:|
Human   519 IDDIVSGHKKKG 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	164/524 (31%)
		Cpn60_TCP1	45..534	CDD:278544	154/492 (31%)
CCT3	NP_005989.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		6/20 (30%)
		chap_CCT_gamma	6..529	CDD:274085	165/528 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100235
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720