Protein Alignment CCT5 and TCP1

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 174/529 - (32%)
• Similarity: 281/529 - (53%)
• Gaps: 31/529 - (5%)

  Fly    28 RITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAKLM 92
            |.||......::|||..||:.:|:||||.||||::|...||||:|||||||:||:||:|..||::
Human    11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVL 75

  Fly    93 VQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQL--DAIAQP 155
            .:|:..||.|:|||||.||::|..||:.|:.|:.:.|||..:..|:.||.:.|::.:  :.|..
Human    76 CELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVN- 139

  Fly   156 FPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNV--ADIE---KKDVNFELIKIETK 215
              .|...::.||..|.|::.|||:.......|.|.|||||.:  .||.   :..||...|   .|
Human   140 --TDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNI---LK 199

  Fly   216 VGGRME-DSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALR 279
            ..||.: :|||:.|..::..:....|||.:.|.|:|.|....:..|.|...::.:|..|....:|
Human   200 AHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIR 264

  Fly   280 EYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIATGGRIVP 344
            :.|.:...:.::::...||.:.:...|.||......::....|||.|...:::.||.|:|..|:.
Human   265 QRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILS 329

  Fly   345 RFEELTPEK------LGVA-GLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAKRS 402
            ....|..|:      ||.| .:|:|.   ...|::::|:..|...:.:|.|||.|..:..|.:||
Human   330 TLANLEGEETFEAAMLGQAEEVVQER---ICDDELILIKNTKARTSASIILRGANDFMCDEMERS 391

  Fly   403 IHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENS 467
            :|||:|||:.:::...:|.||||.|.:.|:.:...|..:.:.||.|...|:.:|..||..||.|:
Human   392 LHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNA 456

  Fly   468 GLHPIETLSELKA----RQVAEKKSSL---GVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLV 525
            .....:.:::|:|    .||..::.:|   |:|.......|.|...|.|....|.:.:..:|:..
Human   457 AQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAA 521

  Fly   526 KMILKIDDV 534
            ..||:|||:
Human   522 ITILRIDDL 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	174/529 (33%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	174/529 (33%)