DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT5 and CCT3

DIOPT Version :9

Sequence 1:	NP_523707.1	Gene:	CCT5 / 36308	FlyBaseID:	FBgn0010621	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001189236.1	Gene:	CCT3 / 42029	FlyBaseID:	FBgn0015019	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	542	Identity:	169/542 - (31%)
Similarity:	287/542 - (52%)	Gaps:	32/542 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIM 79
            :|.::|  .:..||.:|......:|.|.:.||..::|.|||:.:.|:::.|.|.:.:||||..|:
  Fly     6 QPILVL--SQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAIL 68

  Fly    80 KLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQC 144
            :.:.|.|..||.|::::::||:|:|||||.|:||||.:|..||..:.:.|||..|...:..|.:.
  Fly    69 REITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALED 133

  Fly   145 AIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKKDVNFEL 209
            .:..|.: .....:|.|:|..:..:....:|:|.:.|......::|:|||..|...|...:..::
  Fly   134 IVGHLQS-QLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDI 197

  Fly   210 ---IKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTS 271
               .|:|...||.:|:|.::|||:::|.::|.:|.:.:.|.::.:|.|..|..|.:::..:::..
  Fly   198 KRYAKVEKIPGGAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIG 262

  Fly   272 AEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAI 336
            .:|:..:.:.|:|...::...:......|...:.|..|.|.|.||:..:.|:|.:...:...||.
  Fly   263 EQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRIAR 327

  Fly   337 ATGGRIVPRFEELTPEKLGV-AGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAK 400
            |.|..||.|.||||.:.:|. |||......|  .:....:.|||..||.||.|||.:..|:.|.:
  Fly   328 ACGATIVNRTEELTEKDVGTGAGLFEVKKIG--DEYFTFVTECKEPKACTILLRGASKDILNETE 390

  Fly   401 RSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQY--AFRAFSVALESIPLAL 463
            |::.||:.|.|:||.:.|:|.||||.|::        |.||.|.:|.  .:.|.:.|||.||..|
  Fly   391 RNLQDALHVARNLVLEPRLVAGGGAVEMA--------ASQLLTRKQVKGPYTAVAHALEIIPRTL 447

  Fly   464 AENSGLHPIETLSELKARQVAEKKSSL---GVDCMLSGDS----DMKSHNVVESLHSKKQQILLS 521
            |:|.|.:.|..|:.|:|:..:.....:   |:|    |:|    ||...|:.|.|..|.|....:
  Fly   448 AQNCGANTIRALTALRAKHASHTGDGVCAWGID----GESGEIVDMNVKNIWEPLAVKLQTYKTA 508

  Fly   522 TQLVKMILKIDDV--RSKNEGG 541
            .:...::|:|||:  .||..||
  Fly   509 VETAILLLRIDDIVSGSKKRGG 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	165/535 (31%)
CCT5	NP_523707.1	Cpn60_TCP1	45..534	CDD:278544	157/501 (31%)
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	167/537 (31%)
CCT3	NP_001189236.1	TCP1_gamma	7..524	CDD:239453	165/533 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100235
Panther	1	1.100	-	-	P	PTHR11353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.750