DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT5 and CCT7

DIOPT Version :9

Sequence 1:	NP_523707.1	Gene:	CCT5 / 36308	FlyBaseID:	FBgn0010621	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	155/538 - (28%)
Similarity:	276/538 - (51%)	Gaps:	26/538 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RPFIILRDQERQKRITGTDA------IKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTN 73
            :|.|:|..:       |||:      :.::|.|.:.|...::|:|||:|:||::|...|..|::|
  Fly     2 QPQIVLLKE-------GTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISN 59

  Fly    74 DGATIMKLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGF 138
            ||||||||:|:.|..||.:|.:::|||.|:|||||.||:|||..|:|.:..::.|:||..|....
  Fly    60 DGATIMKLLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAI 124

  Fly   139 ELAAQCAIKQLDAIAQPFPVDPKNKEP--LIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIE 201
            ..|.|..:::::.:|.......|:::.  |.:.|.|.:.||::::.....:.:.|||||::.::
  Fly   125 RKALQLCMEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDEL- 188

  Fly   202 KKDVNFELIKIETKVGGRMEDSMLVKGVIVDKTLSHS---QMPKELRNVKLAILTCPFEPPKPKT 263
               :...:|.|:...||.:|:|.||.||...||.|::   ..||...|.|:|:|....|....:.
  Fly   189 ---LPLNMIGIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERD 250

  Fly   264 KHKLDVTSAEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGG 328
            ..::.|.:.::|:.:.:.|.:.....:.::.::||.:.:.:....|.|......:::.....|..
  Fly   251 NAEIRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPE 315

  Fly   329 PEIELIAIATGGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNA 393
            .:::....|.||.::....::.|..||:.....|...|  .::..:.:.|.|:|..|:.||||..
  Fly   316 EDLKRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVG--GERFNLFQGCPNAKTSTLILRGGAE 378

  Fly   394 MIIAEAKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALES 458
            ..:.|.:||:||||.:||..:|...:|.||||.|:..|..:...:..::..||....|.:..||.
  Fly   379 QFLEETERSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEI 443

  Fly   459 IPLALAENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQ 523
            ||..|.:|:|......|::|:.:. |:.....|||......||.....|.|....|...:..:.:
  Fly   444 IPRQLCDNAGFDATNILNKLRQKH-AQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAE 507

  Fly   524 LVKMILKIDD-VRSKNEG 540
            ...|||.:|: ::|...|
  Fly   508 AACMILSVDETIKSPKAG 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	153/532 (29%)
CCT5	NP_523707.1	Cpn60_TCP1	45..534	CDD:278544	145/494 (29%)
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	154/535 (29%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	153/533 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840