DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT5 and cct5

DIOPT Version :9

Sequence 1:	NP_523707.1	Gene:	CCT5 / 36308	FlyBaseID:	FBgn0010621	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_989340.1	Gene:	cct5 / 394966	XenbaseID:	XB-GENE-980275	Length:	541	Species:	Xenopus tropicalis

Alignment Length:	539	Identity:	386/539 - (71%)
Similarity:	481/539 - (89%)	Gaps:	1/539 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAFPGTFAFDEYGRPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSP 65
            |||. ||.|||||||||||::||:|:.|::|.||:|:|||||:.:|:||:|||||.||||:||..
Frog     1 MSAL-GTLAFDEYGRPFIIIKDQDRKSRLSGLDALKSHIMAAKAVANTLRTSLGPNGLDKMMVDK 64

  Fly    66 DGDVTVTNDGATIMKLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIH 130
            ||.||||||||||:.:|:|||:||||||:||:|||||||||||||||||||||||||.|:|||||
Frog    65 DGQVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEQAEQLLDRGIH 129

  Fly   131 PIRIADGFELAAQCAIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVL 195
            |||||||:|.||:.|::.||.|:..|||||:|.||||:.||||||||::|:|||||||:||:::|
Frog   130 PIRIADGYEQAARIAVEHLDKISDSFPVDPENLEPLIRTAMTTLGSKVINRCHRQMAEIAVNSIL 194

  Fly   196 NVADIEKKDVNFELIKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPK 260
            .|||:::|||:|||||:|.||||::||:.|:|||||||..||.||||.:::.|:|||||||||||
Frog   195 TVADMDRKDVDFELIKVEGKVGGKLEDTQLIKGVIVDKDFSHPQMPKVVKDAKIAILTCPFEPPK 259

  Fly   261 PKTKHKLDVTSAEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRW 325
            |||||||||||.|||:||::||:|||.:||||:||.||.||||||||||||||||||.|||||||
Frog   260 PKTKHKLDVTSVEDYKALQKYEKEKFLEMVKQIKDTGANLAICQWGFDDEANHLLLQNELPAVRW 324

  Fly   326 VGGPEIELIAIATGGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRG 390
            |||||||||||||||||||||.||||||||.||:|:|::|||:||:|||||:||||:|||||:||
Frog   325 VGGPEIELIAIATGGRIVPRFCELTPEKLGYAGIVKEISFGTTKDRMLVIEQCKNSRAVTIFIRG 389

  Fly   391 GNAMIIAEAKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVA 455
            ||.|||.|||||:|||:||:|:||:|:|||||||||||||:|||::.||:..:|||||.|||:.|
Frog   390 GNKMIIEEAKRSLHDALCVIRNLVRDNRIVYGGGAAEISCALAVSEAADKCPSLEQYAMRAFADA 454

  Fly   456 LESIPLALAENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILL 520
            ||.||::||||||::||:|::|::::||.|...:||:||:..|.:|||..:|:|:|..|||||.|
Frog   455 LEIIPMSLAENSGMNPIQTMTEVRSKQVKESNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISL 519

  Fly   521 STQLVKMILKIDDVRSKNE 539
            :||:|||||||||:|...|
Frog   520 ATQVVKMILKIDDIRRPGE 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	377/524 (72%)
CCT5	NP_523707.1	Cpn60_TCP1	45..534	CDD:278544	354/488 (73%)
cct5	NP_989340.1	TCP1_epsilon	10..535	CDD:239455	377/524 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	741	1.000	Domainoid score	I103
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6287
Inparanoid	1	1.050	749	1.000	Inparanoid score	I572
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	1	1.000	-	-		FOG0005168
OrthoInspector	1	1.000	-	-		oto104453
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1487
SonicParanoid	1	1.000	-	-		X3688
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110