Protein Alignment CCT5 and HSPD1

DIOPT Version :9

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 140/564 - (24%)
• Similarity: 226/564 - (40%)
• Gaps: 132/564 - (23%)

  Fly    31 GTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEI----AKL 91
            |.||....:.....:|..:..::||||...|:....|...||.||.|:.|.:::..:.    |||
Human    33 GADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKL 97

  Fly    92 MVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLDAIAQPF 156
            :..::.:.::|.|||||...|||.::.::....|.:|.:|:.|..|..||....|.:|...::|.
Human    98 VQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPV 162

  Fly   157 PVDPKNKEPLIQIA-MTTLGSK-IVNKCHRQMAEMAVDAVLNVADIEKKDVNFELIKIETKVGGR 219
                ...|.:.|:| ::..|.| |.|.....|.::....|:.|.|  .|.:|.||..||    |.
Human   163 ----TTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKD--GKTLNDELEIIE----GM 217

  Fly   220 MEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREYEQE 284
            ..|    :|.|....::.|:..|           |.|:               :.|..|.|.:..
Human   218 KFD----RGYISPYFINTSKGQK-----------CEFQ---------------DAYVLLSEKKIS 252

  Fly   285 KFTQMVKQVKDAGA---TLAICQWGFDDEA------NHLLLQQELPAVRWVG-----GPEIELIA 335
            ....:|..::.|.|   .|.|.....|.||      |.|.:..::.||:..|     ..:::.:|
Human   253 SIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA 317

  Fly   336 IATGGRI------VPRFEELTPEKLGVAGLVREMAFGTSKDKML----------------VIEE- 377
            |||||.:      ....|::.|..||..|.|    ..|..|.||                :||:
Human   318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQEIIEQL 378

  Fly   378 ----------------CKNSKAVTIFLRGGNAMI-IAEAKRSIHDAICVVRSLVKDSRIVYGGGA 425
                            .|.|..|.:...||.:.: :.|.|..:.||:...|:.|::. ||.|||.
Human   379 DVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGC 442

  Fly   426 AEISC-----SLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSGLHPIETLSELKARQVAE 485
            |.:.|     ||..|.| ||...:|     .....|:...:.:|:|:|:.     ..|...::.:
Human   443 ALLRCIPALDSLTPANE-DQKIGIE-----IIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQ 496

  Fly   486 KKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMIL 529
            ..|.:|.|.| :||    ..|:||      :.|:..|::|:..|
Human   497 SSSEVGYDAM-AGD----FVNMVE------KGIIDPTKVVRTAL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	140/564 (25%)
		Cpn60_TCP1	45..534	CDD:278544	137/550 (25%)
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	140/564 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810