Protein Alignment CCT5 and Cct8

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001099367.2
• Gene: Cct8 / 288305
• RGDID: 1305452
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 143/524 - (27%)
• Similarity: 263/524 - (50%)
• Gaps: 20/524 - (3%)

  Fly    27 KRITG-TDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAK 90
            |..:| .:|:..:|.|.:::|.|.:|:.||.|::|::::....:.||||.|||::.:||.|..||
  Rat    20 KHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRELEVQHPAAK 84

  Fly    91 LMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQL-DAIAQ 154
            ::|..|..|:.|:||||..|:|.||||||.||.|:..|:....:..|:|:|.:.|.:.| |.:.
  Rat    85 MIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVITGYEIACKKAHEILPDLVC- 148

  Fly   155 PFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQ---MAEMAVDAVLNVADIEKKDVNFELIKIETKV 216
               ...||...:.::: :.|.:.|::|.:..   :|::...|.:::.. :..:.|.:.|::...:
  Rat   149 ---CSAKNLRDVDEVS-SLLRTSIMSKQYGSEEFLAKLISQACVSIFP-DSGNFNVDNIRVCKIL 208

  Fly   217 GGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREY 281
            |..:..|.::.|::..|.....  ...:::.|:|:.:|||:....:||..:.:.:||:.....:.
  Rat   209 GSGVYSSSVLHGMVFKKETEGD--VTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKG 271

  Fly   282 EQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIATGGRIVPRF 346
            |:......||.:...||.:.:......|.|.|...:..:..||.....::..:....|...:|:
  Rat   272 EENLMDAQVKAIAGTGANVIVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPK- 335

  Fly   347 EELTPEKLGVAGLVREMAFGTSKDKMLVI--EECKNSKAVTIFLRGGNAMIIAEAKRSIHDAICV 409
              |||..|...|....:......|..:|:  .|.::....||.|||....::.:.:|::.|.:..
  Rat   336 --LTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNT 398

  Fly   410 VRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSGLHPIET 474
            .:.|.:|.|:|.||||.||..:..:....:....|||||.:.|:.|.|:||.|||||||:...|.
  Rat   399 FKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEV 463

  Fly   475 LSEL-KARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMILKIDD-VRSK 537
            :|:| ...|...|...|.::..:....||...:::::...|...|.|:|.....:|::|. :.:|
  Rat   464 ISKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIMAK 528

  Fly   538 NEGG 541
            ..||
  Rat   529 PAGG 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	140/517 (27%)
Cct8	NP_001099367.2	chap_CCT_theta	10..539	CDD:274087	143/524 (27%)