Protein Alignment CCT5 and Tcp1

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_036802.1
• Gene: Tcp1 / 24818
• RGDID: 3832
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 180/544 - (33%)
• Similarity: 292/544 - (53%)
• Gaps: 40/544 - (7%)

  Fly    28 RITGTDAIKT-HIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAKL 91
            |.|| :||:: ::|||..||:.:|:||||.||||::|...||||:|||||||:||:||:|..||:
  Rat    11 RSTG-EAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKV 74

  Fly    92 MVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQL--DAIAQ 154
            :.:|:..||.|:|||||.||::|..||:.|:.|:.:.|||..:..|:.||.:.|::.:  :.|..
  Rat    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIIN 139

  Fly   155 PFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNV--ADIE---KKDVNFELIKIET 214
               .|...::.||..|.|::.|||:.......|.|.|||||.|  .||.   :..||...|   .
  Rat   140 ---TDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSVNI---L 198

  Fly   215 KVGGRME-DSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRAL 278
            |..||.: :|||:.|..::..:....|.|.:.|.|:|.|....:..|.|...::.:|..|....:
  Rat   199 KAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQI 263

  Fly   279 REYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIATGGRIV 343
            |:.|.:...:.::::...||.:.:...|.||......::....|||.|...:::.||.|:|..|:
  Rat   264 RQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASIL 328

  Fly   344 PRFEELTPEK------LGVA-GLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAKR 401
            .....|..|:      ||.| .:|:|.   ...|::::|:..|...:.:|.|||.|..:..|.:|
  Rat   329 STLANLEGEETFEATMLGQAEEVVQER---ICDDELILIKNTKARTSASIILRGANDFMCDEMER 390

  Fly   402 SIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAEN 466
            |:|||:|||:.:::...:|.||||.|.:.|:.:...|..:.:.||.|...|:.:|..||..||.|
  Rat   391 SLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455

  Fly   467 SGLHPIETLSELKA----RQVAEKKSSL---GVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQL 524
            :.....:.:::|:|    .||..::.:|   |:|.:.....|.|...|.|....|.:.:..:|:.
  Rat   456 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEA 520

  Fly   525 VKMILKIDDV-----RSKNE--GG 541
            ...||:|||:     .||::  ||
  Rat   521 AITILRIDDLIKLHPESKDDKHGG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	176/535 (33%)
Tcp1	NP_036802.1	TCP1_alpha	9..535	CDD:239451	176/533 (33%)