Protein Alignment CCT5 and Cct8l1

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_941023.1
• Gene: Cct8l1 / 242891
• MGIID: 2685289
• Length: 562
• Species: Mus musculus
• Alignment Length: 534
• Identity: 132/534 - (24%)
• Similarity: 239/534 - (44%)
• Gaps: 93/534 - (17%)

  Fly    41 AARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEIAKLMVQLSQSQDDEIGD 105
            ||:.:||.:::..||.|..|.:|:..|:...|...|.|:|.::::|..|:.:.:|:|:|.:..||
Mouse    48 AAQTLASIIRSCYGPFGRQKFLVTAKGETVCTGHAAAILKALDLEHPAAQFVQELAQTQVENAGD 112

  Fly   106 GTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLDAIAQPFPVDPKNKEPLIQIA 170
            ||..||:|..||||||..|:..|:.|.::.:.|..|....:..|.:                 :|
Mouse   113 GTVFVVLLTEALLEQAHYLLWAGLTPTQLREAFATATAEVLTALPS-----------------LA 160

  Fly   171 MTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKKDVNFELI--------------KIETKV----- 216
            :.:||.       .:....|:.:|::...:...|...:|:              |.|:.|
Mouse   161 IRSLGP-------LEDPSWALYSVISTHTLSNSDYLTKLVAQACWVSREPNGSFKPESIVVCVLQ 218

  Fly   217 GGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREY 281
            ||::.||.:..||.:...|. .|..:.|.:.::|:..|||.|..|.|.....:::.|
Mouse   219 GGKLTDSRIFPGVAIAGKLC-GQKTEVLGDARVALFNCPFGPTNPFTLATPRLSNPE-------- 274

  Fly   282 EQEKFTQMVKQVKDAGATLAICQWGFD-----------DEANH---LLLQQELPAVRWVGGPEIE 332
            |..:|.:..:||:...|.|||......           |:||:   :::|.:       ...||.
Mouse   275 ELLRFRKQTEQVEKEIAQLAIMDINVAVVLGEVNEKSVDQANYCGIMVIQAK-------SRKEIV 332

  Fly   333 LIAIATG----GRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKA--VTIFLRGG 391
            .::...|    ||::|      |.:.|....|....||   |..:|:.|.::..|  :::.|||.
Mouse   333 YLSEKLGTPLLGRVLP------PLEPGKCHKVYRKEFG---DTAVVMFEWEHEIAPFLSVVLRGP 388

  Fly   392 NAMIIAEAKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVAL 456
            ....:..|:::::..|.....|.:|.|::.|.||.|::.:..:..:..:||.....||:||:.||
Mouse   389 TIQGLRVAEQAVYYGIDAFSQLCQDPRLLPGAGATEMALAKMLVDKGSRLSGPNGLAFQAFAQAL 453

  Fly   457 ESIPLALAENSGLHPIETLSELKA-RQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILL 520
            .|:|..||||:||.....::||.. .|.......:|.|    |..::....:.:.|.:|.|.:..
Mouse   454 SSLPKTLAENAGLAAQSVMAELSGFHQAGNFFVGVGTD----GLVNVTHEGIWDILRTKAQGLQA 514

  Fly   521 STQLVKMILKIDDV 534
            ..:||:.::.:|.:
Mouse   515 VAELVQQLVTVDQI 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	132/534 (25%)
Cct8l1	NP_941023.1	Cpn60_TCP1	52..532	CDD:395068	130/530 (25%)