Protein Alignment CCT5 and cct3

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_775357.1
• Gene: cct3 / 192327
• ZFINID: ZDB-GENE-020419-5
• Length: 543
• Species: Danio rerio
• Alignment Length: 541
• Identity: 166/541 - (30%)
• Similarity: 296/541 - (54%)
• Gaps: 26/541 - (4%)

  Fly    14 GRPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATI 78
            |||.::|  .:..||.:|......:|.||:.||..::|.|||:.:.|:::.|.|.:.:||||..|
Zfish     3 GRPVLVL--SQNIKRESGRKVQIGNISAAKTIADIIRTCLGPRAMMKMLLDPMGGIVMTNDGNAI 65

  Fly    79 MKLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQ 143
            ::.::|.|..||.|:::|::||:|:|||||.|::|||.:|..||..:::.:||..:...:..|..
Zfish    66 LREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEQFLEQQMHPTVVIGAYRQALD 130

  Fly   144 CAIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNV---------AD 199
            ..:..|..|:.  |||..|::.:::|..:.:.:|.:::.......:|:|||..|         .|
Zfish   131 DMLNILKDIST--PVDVSNRDMMLKIINSAINTKALSRWSTLACNIALDAVRTVELDENGREEID 193

  Fly   200 IEKKDVNFELIKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTK 264
            |:|      ..|:|...||.:|||.:::||:|:|.::|.:|.:.::|.::.:|.|..|..|.:::
Zfish   194 IKK------YAKVEKVPGGIIEDSCVLRGVMVNKDVTHPRMRRLIKNPRIVLLDCSLEYKKGESQ 252

  Fly   265 HKLDVTSAEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGP 329
            ..:::...||:..:.:.|:|...|:.:.:......|...:.|..|.|.|.|::..:.|:|.:...
Zfish   253 TDIEIAREEDFARILQMEEEYVQQICEDIIRLKPDLIFTEKGISDLAQHYLMKANITAIRRIRKT 317

  Fly   330 EIELIAIATGGRIVPRFEELTPEKLGV-AGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNA 393
            :...||.|.|.||..|.:|||...:|. .||......|  .:....:.|||:.||.||.|||.:.
Zfish   318 DNNRIARACGARIASRTDELTENDVGTGTGLFEVKKIG--DEYFTFVTECKDPKACTILLRGASK 380

  Fly   394 MIIAEAKRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALES 458
            .|:||.:|::.||:.|.|:::.|..::.||||.|:..|..:.:.:..::.:||:.:||.:.|||.
Zfish   381 EILAEVERNLQDAMQVCRNVLLDPYLLPGGGAVEMEVSHRLTERSRAMTGVEQWPYRAVAQALEV 445

  Fly   459 IPLALAENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQ 523
            :|..|.:|.|...|..|:.|:|:...|..||.||:......:||:...:.|.|..|.|....:.:
Zfish   446 VPRTLIQNCGASAIRVLTSLRAKHTQEGNSSWGVNGETGTLADMEQLGIWEPLAVKAQTYKTAVE 510

  Fly   524 LVKMILKIDDV----RSKNEG 540
            ...::|:|||:    :.|.:|
Zfish   511 TAILLLRIDDIVSGHKKKGDG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	164/535 (31%)
cct3	NP_775357.1	chap_CCT_gamma	5..528	CDD:274085	162/534 (30%)