Protein Alignment CCT5 and Hspd1

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_034607.3
• Gene: Hspd1 / 15510
• MGIID: 96242
• Length: 573
• Species: Mus musculus
• Alignment Length: 582
• Identity: 137/582 - (23%)
• Similarity: 230/582 - (39%)
• Gaps: 126/582 - (21%)

  Fly    31 GTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVDHEI----AKL 91
            |.||....:.....:|..:..::||||...|:....|...||.||.|:.|.:::..:.    |||
Mouse    33 GADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKL 97

  Fly    92 MVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLDAIAQPF 156
            :..::.:.::|.|||||...|||.::.::....|.:|.:|:.|..|..||....|.:|...::|.
Mouse    98 VQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPV 162

  Fly   157 PVDPKNKEPLIQIA-MTTLGSK-IVNKCHRQMAEMAVDAVLNVADIEKKDVNFELIKIETKVGGR 219
                ...|.:.|:| ::..|.| |.|.....|.::....|:.|.|  .|.:|.||..||    |.
Mouse   163 ----TTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKD--GKTLNDELEIIE----GM 217

  Fly   220 MEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREYEQE 284
            ..|    :|.|....::.|:..|           |.|:               :.|..|.|.:..
Mouse   218 KFD----RGYISPYFINTSKGQK-----------CEFQ---------------DAYVLLSEKKIS 252

  Fly   285 KFTQMVKQVKDAGA---TLAICQWGFDDEA------NHLLLQQELPAVRWVG-----GPEIELIA 335
            ....:|..::.|.|   .|.|.....|.||      |.|.:..::.||:..|     ..:::.:|
Mouse   253 SVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA 317

  Fly   336 IATGGRIVP------RFEELTPEKLGVAGLVREMAFGTSKDKMLV------------IEE----- 377
            |||||.:..      ..|::....||..|.|    ..|..|.||:            |:|
Mouse   318 IATGGAVFGEEGLNLNLEDVQAHDLGKVGEV----IVTKDDAMLLKGKGDKAHIEKRIQEITEQL 378

  Fly   378 ----------------CKNSKAVTIFLRGGNAMI-IAEAKRSIHDAICVVRSLVKDSRIVYGGGA 425
                            .|.|..|.:...||.:.: :.|.|..:.||:...|:.|::. ||.|||.
Mouse   379 DITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGC 442

  Fly   426 AEISC-----SLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSGLHPIETLSELKARQVAE 485
            |.:.|     ||..|.| ||...:|     ....||:...:.:|:|:|:.     ..|...::.:
Mouse   443 ALLRCIPALDSLKPANE-DQKIGIE-----IIKRALKIPAMTIAKNAGVE-----GSLIVEKILQ 496

  Fly   486 KKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMILKIDDV-----RSKNEGGM 542
            ..|.:|.|.||....:|....:::.....:..:|.:..:..::...:.|     :.:.:.||
Mouse   497 SSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGM 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	135/574 (24%)
Hspd1	NP_034607.3	GroEL	28..548	CDD:239460	135/570 (24%)