Protein Alignment CCT5 and Cct3

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_033966.1
• Gene: Cct3 / 12462
• MGIID: 104708
• Length: 545
• Species: Mus musculus
• Alignment Length: 532
• Identity: 169/532 - (31%)
• Similarity: 307/532 - (57%)
• Gaps: 12/532 - (2%)

  Fly    15 RPFIILRDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIM 79
            ||.::|  .:..||.:|......:|.||:.||..::|.||||.:.|:::.|.|.:.:||||..|:
Mouse     5 RPVLVL--SQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAIL 67

  Fly    80 KLMEVDHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQC 144
            :.::|.|..||.|:::|::||:|:|||||.|::|||.:|..||..:::.:||..:...:.:|...
Mouse    68 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMALDD 132

  Fly   145 AIKQLDAIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIE--KKDVNF 207
            .|..|..|:.  |||..|:|.::.|..:::.:|::::.......:|:|||..|...|  :|:::.
Mouse   133 MISTLKKIST--PVDVNNREMMLSIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDI 195

  Fly   208 -ELIKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTS 271
             :..::|...||.:|||.:::||:::|.::|.:|.:.::|.::.:|....|..|.:::..:::|.
Mouse   196 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITR 260

  Fly   272 AEDYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAI 336
            .||:..:.:.|:|...|:.:.:......:.|.:.|..|.|.|.|::..:.|:|.|...:...||.
Mouse   261 EEDFTRILQMEEEYIHQLCEDIIQLKPDVVITEKGISDLAQHYLMRANVTAIRRVRKTDNNRIAR 325

  Fly   337 ATGGRIVPRFEELTPEKLGV-AGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAK 400
            |.|.|||.|.|||..:.:|. |||:.....|  .:....|.:||:.||.||.|||.:..|::|.:
Mouse   326 ACGARIVSRPEELREDDVGTGAGLLEIKKIG--DEYFTFITDCKDPKACTILLRGASKEILSEVE 388

  Fly   401 RSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAE 465
            |::.||:.|.|:::.|.::|.||||:|::.:.|:.:::..::.:||:.:||.:.|||.||..|.:
Mouse   389 RNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQ 453

  Fly   466 NSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMILK 530
            |.|...|..|:.|:|:...|...:.||:.......|||...:.|.|..|.|....:.:...::|:
Mouse   454 NCGASTIRLLTSLRAKHTQESCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLR 518

  Fly   531 IDDVRS--KNEG 540
            |||:.|  |.:|
Mouse   519 IDDIVSGHKKKG 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	166/524 (32%)
Cct3	NP_033966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		6/20 (30%)
		chap_CCT_gamma	6..529	CDD:274085	167/528 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		2/5 (40%)