Protein Alignment CCT5 and Cct2

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_031662.2
• Gene: Cct2 / 12461
• MGIID: 107186
• Length: 535
• Species: Mus musculus
• Alignment Length: 521
• Identity: 175/521 - (33%)
• Similarity: 277/521 - (53%)
• Gaps: 25/521 - (4%)

  Fly    22 DQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSP--DGDVTVTNDGATIMKLMEV 84
            |:||.:     .|..:..:.|..|...:|::|||||:|||::|.  |..:.||||||||:|.:.|
Mouse    17 DEERAE-----TARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVTNDGATILKNIGV 76

  Fly    85 DHEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQL 149
            |:..||::|.:|:.||||:|||||.|.|||..||.:||.||.:.|||..|..|:..|.:.|.:.|
Mouse    77 DNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIISGWREATKAAREAL 141

  Fly   150 DAIAQPFPVDPKNKE-----PLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVADIEKKDVNFEL 209
            .:.|    ||..:.|     .|:.||.|||.||::........::||:|||.:    |...|.|.
Mouse   142 LSSA----VDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL----KGSGNLEA 198

  Fly   210 IKIETKVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKT-KHKLDVTSAE 273
            |.:..|:||.:.||.|.:|.::||.:..:| ||.:.|.|:.|.....:..|.|. ..::.|.|..
Mouse   199 IHVIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENAKILIANTGMDTDKIKIFGSRVRVDSTA 262

  Fly   274 DYRALREYEQEKFTQMVKQVKDAGATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIAT 338
            ....:...|:||..:.|:::...|....|.:....:....|.....:.|:.......:|.:|:.|
Mouse   263 KVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVT 327

  Fly   339 GGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAKRSI 403
            ||.|...|:.....|||...|:.|:..|  :||::........:|.||.|||....|:.||:||:
Mouse   328 GGEIASTFDHPELVKLGSCKLIEEVMIG--EDKLIHFSGVALGEACTIVLRGATQQILDEAERSL 390

  Fly   404 HDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALAENSG 468
            |||:||:...|||.|.|||||.:|:..:.||.:.|::....|..|..:|:.||..:|..:|:|:|
Mouse   391 HDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESFAKALRMLPTIIADNAG 455

  Fly   469 LHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMILKIDD 533
            ....:.:::|:|.. :|...:.|:|.......||....:.||...|:|.:|.:.:..::||::|:
Mouse   456 YDSADLVAQLRAAH-SEGHITAGLDMKEGTIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDN 519

  Fly   534 V 534
            :
Mouse   520 I 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	175/521 (34%)
Cct2	NP_031662.2	TCP1_beta	11..527	CDD:239452	175/521 (34%)