Protein Alignment CCT5 and CCT4

DIOPT Version :10

• Sequence 1: NP_523707.1
• Gene: CCT5 / 36308
• FlyBaseID: FBgn0010621
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_006421.2
• Gene: CCT4 / 10575
• HGNCID: 1617
• Length: 539
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 195/525 - (37%)
• Similarity: 313/525 - (59%)
• Gaps: 27/525 - (5%)

  Fly    21 RDQERQKRITGTDAIKTHIMAARQIASTLKTSLGPKGLDKIMVSPDGDVTVTNDGATIMKLMEVD 85
            ||:..|.|.       ::|.||:.:|..::|||||||:||::....||||:|||||||:|.|:|.
Human    27 RDKPAQIRF-------SNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVL 84

  Fly    86 HEIAKLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAEGLIDRGIHPIRIADGFELAAQCAIKQLD 150
            |..|:::|:||::||.|.|||||.||::||:||:....|:.:||||..|::.|:.|.:..|:.|.
Human    85 HPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILT 149

  Fly   151 AIAQPFPVDPKNKEPLIQIAMTTLGSKIVNKCHRQMAEMAVDAVLNVAD-IEKKDVNFELIKIET 214
            .:::  ||:..::|.|:..|.|:|.||:|::....::.|:|:||:.|.| .....|:...|||..
Human   150 DMSR--PVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVK 212

  Fly   215 KVGGRMEDSMLVKGVIVDKTLSHSQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDY---- 275
            |:||.::|..||:|:::.:.:|:|.:.: :...|:.::......||....:::.|:   ||
Human   213 KLGGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQIVVS---DYAQMD 273

  Fly   276 RALREYEQEKFTQMVKQVKDAGATLAICQW-----GFDDEANHLLLQQELPAVRWVGGPEIELIA 335
            |.||| |:.....:|||:|..|..:.:.|.     ...|.|.|.|.:.::..::.:...:||.|.
Human   274 RVLRE-ERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFIC 337

  Fly   336 IATGGRIVPRFEELTPEKLGVAGLVREMAFGTSKDKMLVIEECKN-SKAVTIFLRGGNAMIIAEA 399
            ...|.:.|...::.|.:.||.|.|..|:....| .|:|.|..|.: .|.|||.:||.|.::|.||
Human   338 KTIGTKPVAHIDQFTADMLGSAELAEEVNLNGS-GKLLKITGCASPGKTVTIVVRGSNKLVIEEA 401

  Fly   400 KRSIHDAICVVRSLVKDSRIVYGGGAAEISCSLAVAKEADQLSTLEQYAFRAFSVALESIPLALA 464
            :||||||:||:|.|||...::.||||.||..:|.:.:.:..||.:|.|..|||:.|:|.||..||
Human   402 ERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLA 466

  Fly   465 ENSGLHPIETLSELKARQVAEKKSSLGVDCMLSGDSDMKSHNVVESLHSKKQQILLSTQLVKMIL 529
            ||:||:||.|::||:.|. |:.:.:.|::....|.|::....||:.|......:.|:|:.|:.||
Human   467 ENAGLNPISTVTELRNRH-AQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSIL 530

  Fly   530 KIDDV 534
            |||||
Human   531 KIDDV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT5	NP_523707.1	TCP1_epsilon	11..536	CDD:239455	195/525 (37%)
CCT4	NP_006421.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		1/1 (100%)
		TCP1_delta	25..538	CDD:239454	195/525 (37%)