Protein Alignment CG8878 and TTBK1

DIOPT Version :9

• Sequence 1: NP_001260913.1
• Gene: CG8878 / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_016866853.1
• Gene: TTBK1 / 84630
• HGNCID: 19140
• Length: 1409
• Species: Homo sapiens
• Alignment Length: 1111
• Identity: 212/1111 - (19%)
• Similarity: 328/1111 - (29%)
• Gaps: 442/1111 - (39%)

  Fly   118 VLSKAWRLGRPIGKGNFGEIFLASD----DTVC--PASSETAKYVVKIEPHSNGPLFVEIHCLIN 176
            |:...|::.:.||.|.||||:.|.|    :.|.  ..|::..|.|:|:|.           .::.
Human    29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEV-----------AVLK 82

  Fly   177 TSRNNDLSDAAEDAASLPAPQTHVLSRGPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLI 241
            ..:..|                ||.         .||..|.    :.::.::|:....|:|..|
Human    83 KLQGKD----------------HVC---------RFIGCGR----NEKFNYVVMQLQGRNLADL- 117

  Fly   242 KNSRVQQKSLLVLAV------HIINVLENLHDKGYCHNDIKAQNLMVS-------KCKY----LR 289
              .|.|.:....|:.      .|:..:|.:|..|:.|.|||..|..:.       ||..    |.
Human   118 --RRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA 180

  Fly   290 RQ-------VVPKGNGYEDHYEEKQQTTDSGNSSEQETNDD--DYFLKSEKFAL-----KKIVDI 340
            ||       |.|..|........:..:.::..:.|...:||  ..|....:||:     :||.|
Human   181 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKD- 244

  Fly   341 KQDEDEDDEDFDDGATSNSNNSN---------SLD------------VFHTPVNKKRSARN---- 380
            |:......|.::.........|.         |||            ||...:.::..|.|
Human   245 KEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFD 309

  Fly   381 --------AIQFSGSNPVRACRREKRNSMYEEM----VKSHYLRPTKRISYREEFNEDGYPKETA 433
                    .:..|.|.|.:...|:.. :|:..:    |....||         |..||....|..
Human   310 WEKAGTDALLSTSTSTPPQQNTRQTA-AMFGVVNVTPVPGDLLR---------ENTEDVLQGEHL 364

  Fly   434 ENSDESPESSDNESDEFIPPSSRRSVIKRGRSAQI------------------------------ 468
            .:.:.:|........|.:.||........|..|::
Human   365 SDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKVTAARAKGVGGLF 429

  Fly   469 -----------ATPKKTPV-----------------------STRASRQEKVKKEPNGDQKLRSR 499
                       ..|.|.||                       .:.:|......:.|:...:|.|.
Human   430 SHPRFPALCPCPVPPKHPVPGHLPACPASVSRSLPALASLCLPSSSSSVSFTLRRPSAHSRLISP 494

  Fly   500 GSKH--LDNNPTEYKFLPTEEEHVFLIDFGLASKFQDRGVHRPF---------------IMDQRR 547
            .|.|  |..:|.      .|||             |.||:..|.               .:..||
Human   495 SSWHSPLLQSPC------VEEE-------------QSRGMGVPSSPVRAPPDSPTTPVRSLRYRR 540

  Fly   548 AH----------DGTLEFTSRDAHL---GAHSRRSDLECLGY--NLLYWSEGYLPWK-----DVA 592
            .:          ||.:|...|.:.:   |:.||::   |...  .:|....|:...:     ||:
Human   541 VNSPESERLSTADGRVELPERRSRMDLPGSPSRQA---CSSQPAQMLSVDTGHADRQASGRMDVS 602

  Fly   593 QQQQQEKVHRA--------------KELFMTDVPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERP 643
            ...:||.:..|              ||..:.|....|:.|.....|...|         ...|.|
Human   603 ASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSG---------TTDEEP 658

  Fly   644 NYERYRKIFKREYQRLGYDPC------QMRLSSEEILR----------------TCVSTKDVVDG 686
            ...|.......|.:|||.:|.      .|:..:||.|:                ...:::....|
Human   659 EELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPG 723

  Fly   687 S----------------------KCDIFELNNKAAVN-VMRNSTLSTPFQEHS-----------L 717
            |                      :..:|.:.....|| :.|...||.|:|:..           |
Human   724 SPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARL 788

  Fly   718 TNRVSPKNLRSKSNKKTTKKKFSWAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKP 782
            .|||               ::..::.:|...|.                 .||....|:. .||
Human   789 LNRV---------------RRVGFSHMLLTTPQ-----------------VPLAPVQPQA-NGK- 819

  Fly   783 TYAILDMEQRRREKGLVVQEHIEEEEEDADEDDEEENQEAMDIDQEEDGEAA------------- 834
                   |:...|     :|..||||||.:|::|||.:|..:.::||:.|.|
Human   820 -------EEEEEE-----EEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPR 872

  Fly   835 --DSAEGEDES-DRSMEG--SDCSDHSQKRARGRPK--------------------GTSRKQTTS 874
              .|:||.:.| |||.||  |......||.:|||..                    |..:|...:
Human   873 SGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVT 937

  Fly   875 RQAQP-------------HQNQPPVKVHRGVGRPGKNSGVVK-----------LAAGAVSKNRTT 915
            .:..|             |:...|......|..||..|.|:|           |.||.|    ||
Human   938 AELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTV----TT 998

  Fly   916 PLSAVA 921
            .:..||
Human   999 GVGGVA 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	40/186 (22%)
		SPS1	123..>284	CDD:223589	38/179 (21%)
		SPS1	<491..756	CDD:223589	65/371 (18%)
		PKc_like	<517..652	CDD:304357	34/183 (19%)
TTBK1	XP_016866853.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900